A convenient synthesis of 3-methyleneoxindoles: Cytotoxic metabolites of indole-3-acetic acids
3-Methyleneoxindole is a cytotoxic metabolite of indole-3-acetic acid with potential for use in cancer therapy. This species and ring-substituted analogues are conveniently synthesised from the corresponding isatins via a Peterson olefination.
Rossiter, Sharon
p. 4671 - 4673
(2007/10/03)
Synthetic method for indol-2(3H)-ones
A two-step process for the synthesis of certain indol-2(3H)-ones from indoles, and the 3,3-dibromoindol-2(3H)-ones which are intermediates in that process.
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(2008/06/13)
OXIDATION OF INDOLES WITH PYRIDINIUM BROMIDE PERBROMIDE. A SIMPLE AND EFFICIENT SYNTHESIS OF 7-AZAOXINDOLES
Indoles and azaindoles on treatment with pyridinium bromide perbromide (PBPB) in t-butanol give 3,3-dibromooxindoles which, upon further reduction, yield the corresponding oxindoles.
Marfat, Anthony,Carta, Michael P.
p. 4027 - 4030
(2007/10/02)
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