cas 111821-58-0, (S)-(-)-3-AMINO-1-HYDROXYPYRROLIDIN-2-ONE | Articles data ｜lookchem

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111821-58-0

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Resolution and synthesis of the individual enantiomers of the glycine antagonist 3-amino-1-hydroxypyrrolidin-2-one (HA-966)
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Williams,Leeson,Hannah,Baker
p. 1740 - 1742
(2007/10/02)

4-N-Hydroxy-L-2,4-diaminobutyric acid. A strong inhibitor of glutamine synthetase
Analogues of glutamic acid were synthesized and evaluated for their inhibitory activity toward glutamine synthetase (EC 6.3.1.2; GS). The title compound, 4-N-hydroxy-L-2,4-diaminobutyric acid (NH-DABA), showed a potent inhibitory activity against GS from
Fushiya,Maeda,Funayama,Nozoe
p. 480 - 483
(2007/10/02)

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Chemical Properties

Melting Point: 166℃
Boiling Point: 258.6 °C at 760 mmHg
Flash Point:110.2 °C
Density: 1.436 g/cm³
Storage Temp.:Store at RT
PKA: 7.19±0.20(Predicted)
PSA: 66.56000
LogP: -0.42660

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