Enantioselective three-component reaction for the preparation of β-amino-α-hydroxy esters
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Zhou, Jing,Xu, Xinfang,Hu, Wenhao
p. 418 - 426
(2014/04/03)
Cooperative catalysis with chiral Bronsted acid-Rh 2(OAc)4: Highly enantioselective three-component reactions of diazo compounds with alcohols and imines
An asymmetric three-component reaction of diazo compounds and alcohols with imines catalyzed cooperatively by a rhodium complex and a chiral Bronsted acid provides a general and efficient entry to β-amino-α-hydroxyl acid derivatives in high yields with excellent stereoselectivities. Copyright