101072-61-1

1,4-Dihydropyridine-3-carboxylic acid piperazides of the formula STR1 in which R1 is CN or alkyl, preferably methyl, R2 is H, CN, NO2 or preferably carboxyalkyl, R3 is aryl or heterocyclic, and R4 is alkyl, cycloalkyl, aryl or an acyl radical, and physiologically acceptable salts thereof, are circulation active. Novel intermediates are also provided.