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| Name |
Benzedrine sulfate |
EINECS | N/A |
| CAS No. | 60-13-9 | Density | N/A |
| PSA | 109.00000 | LogP | 2.70460 |
| Solubility | N/A | Melting Point |
280 - 281oC |
| Formula | C9H13N.1/2H2O4S | Boiling Point | 407.2oC at 760 mmHg |
| Molecular Weight | 368.497 | Flash Point | 239.4oC |
| Transport Information | N/A | Appearance | N/A |
| Safety | Risk Codes | R25; R39/23/24/25; R23/24/25; R11 | |
| Molecular Structure |
|
Hazard Symbols |
 T, F
|
| Synonyms |
benzies;1-methyl-2-phenyl-ethylamine,sulfate (1:2);leodrin;astedin;fenara;Benzeneethanamine, a-methyl-, sulfate (2:1);levonor;betafen;d-amphetamine sulphate;noclon;alentol;peaches;ortenal; |
Benzedrine sulfate Chemical Properties
IUPAC Name: 1-phenylpropan-2-amine; sulfuric acid
Synonyms of Benzedrine sulfate (CAS NO.60-13-9): Amphetamine sulfate [USP] ; Adderall ; (+-)-2-Amino-1-phenylpropane sulfate ; (+-)-Amphetamine sulfate ; (+-)-Phenisopropylamine sulfate ; (+-)-alpha-Methylphenethylamine sulfate (2:1) ; 1-Phenyl-2-aminopropane sulfate ; Adiparthrol ; Aktedrin ; Alentol ; Amphamine sulfate ; Amphetamine sulfate ; Amphetamine sulphate ; Amphetamini sulfas ; Amphetaminium sulfuricum ; Amphoids-S ; Anara ; Astedin ; Bennie ; Benzafinyl ; Benzedrine ; Benzies ; Benzpropamine ; Betafen ; Betaphen ; Bluzedrin ; CCRIS 3644 ; CERM 1767 ; Cartwheels ; Centramina ; DL-1-Phenyl-2-aminopropane sulfate ; DL-Amphetamine hydrogen sulfate ; Desoxynorephedrine sulfate ; Dietamine ; Durophet ; EINECS 200-457-8 ; Euphobine ; Euphodyn ; Fabedrine ; Fenamin ; Fenara ; Fenedrin ; Fenopromin sulfate ; Halloo-wach ; Ibiozedrine ; Leodrin ; Mimetina ; Monetamine ; NCI-C55710 ; NSC 170999 ; Noclon ; Oraldrina ; Ortenal ; Peaches ; Penamine (VAN) ; Pharmamedrine ; Phenamine (sympathomimetic) ; Phenamine sulfate ; Phenaminum ; Phenisopropylamine sulfate ; Phenopromin ; Phenpromin ; Racephen ; Sedolin ; UNII-6DPV8NK46S ; Vapedrine ; Weckamine ; Zedrine ; alpha-Methylphenethylamine sulfate, (+-)- ; dl-Amphetamine sulphate ; dl-Phenamine sulfate ; dl-alpha-Methylphenethylamine sulfate ;
Deleted Registry Number(s): 156-31-0
CAS NO: 60-13-9
Molecular Formula of Benzedrine sulfate (CAS NO.60-13-9): C18H28N2O4S
Molecular Weight: 368.4909
H bond acceptors: 1
H bond donors: 2
Freely Rotating Bonds: 3
Polar Surface Area: 3.24 Å2
Flash Point: 87.4°C
Enthalpy of Vaporization: 43.77 kJ/mol
Boiling Point: 201.5 °C at 760 mmHg
Vapour Pressure: 0.307 mmHg at 25°C
Molecular Structure:
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Benzedrine sulfate Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| chicken | LD50 | intraperitoneal | 125mg/kg (125mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) | Toxicology and Applied Pharmacology. Vol. 2, Pg. 558, 1960. |
| chicken | LD50 | intravenous | 70mg/kg (70mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) | Toxicology and Applied Pharmacology. Vol. 2, Pg. 558, 1960. |
| dog | LD50 | intravenous | 6mg/kg (6mg/kg) | Proceedings of the Society for Experimental Biology and Medicine. Vol. 118, Pg. 557, 1965. | |
| dog | LD50 | oral | 23mg/kg (23mg/kg) | Proceedings of the Society for Experimental Biology and Medicine. Vol. 118, Pg. 557, 1965. | |
| domestic animals - goat/sheep | LDLo | subcutaneous | 15mg/kg (15mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION | American Journal of the Medical Sciences. Vol. 198, Pg. 785, 1939. |
| frog | LD50 | parenteral | 280mg/kg (280mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Journal of Pharmacology and Experimental Therapeutics. Vol. 76, Pg. 375, 1942. |
| guinea pig | LD50 | subcutaneous | 105mg/kg (105mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 137, Pg. 375, 1962. | |
| guinea pig | LDLo | intraperitoneal | 50mg/kg (50mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 100, Pg. 267, 1950. | |
| human | TDLo | oral | 41mg/kg (41mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: ANOREXIA (HUMAN CARDIAC: CHANGE IN RATE | Klinische Wochenscrift. Vol. 17, Pg. 1580, 1938. |
| monkey | LDLo | subcutaneous | 5mg/kg (5mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION | American Journal of the Medical Sciences. Vol. 198, Pg. 785, 1939. |
| mouse | LD50 | intraperitoneal | 13mg/kg (13mg/kg) | Pharmaceutical Chemistry Journal Vol. 26, Pg. 430, 1992. | |
| mouse | LD50 | intravenous | 31800ug/kg (31.8mg/kg) | BEHAVIORAL: EXCITEMENT BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) | Toxicology and Applied Pharmacology. Vol. 2, Pg. 558, 1960. |
| mouse | LD50 | oral | 24mg/kg (24mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS | Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 711, 1963. |
| mouse | LD50 | subcutaneous | 7mg/kg (7mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 170, Pg. 428, 1967. | |
| rabbit | LDLo | intravenous | 22mg/kg (22mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal de Physiologie et de Pathologie Generale. Vol. 37, Pg. 597, 1939. |
| rat | LD50 | intraperitoneal | 125mg/kg (125mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal of Pharmacology and Experimental Therapeutics. Vol. 132, Pg. 97, 1961. |
| rat | LD50 | oral | 55mg/kg (55mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS | Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 711, 1963. |
| rat | LD50 | subcutaneous | 160mg/kg (160mg/kg) | BEHAVIORAL: EXCITEMENT LIVER: OTHER CHANGES | Annals of Internal Medicine. Vol. 10, Pg. 1874, 1937. |
Benzedrine sulfate Safety Profile
Hazard Codes of Benzedrine sulfate (CAS NO.60-13-9): 
T,
F
Risk Statements: 39-23/24/25-11
R39: Danger of very serious irreversible effects.
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed.
R11: Highly flammable.
Safety Statements: 45-36/37-16
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37: Wear suitable protective clothing and gloves.
S16: Keep away from sources of ignition.
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: SI1750000
HazardClass: 6.1(b)
PackingGroup: III
A poison via ingestion, intraperitoneal, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of SOx and NOx. See also BENZEDRINE and SULFATES.
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