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| Name |
Amfepramone hydrochloride |
EINECS | 205-156-5 |
| CAS No. | 134-80-5 | Density | 0.972g/cm3 |
| PSA | 20.31000 | LogP | 3.40160 |
| Solubility | N/A | Melting Point |
180-1810C |
| Formula | C13H19 N O . Cl H | Boiling Point | 292°Cat760mmHg |
| Molecular Weight | 241.761 | Flash Point | 95.4°C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits very toxic fumes of HCl, NH3, and NOx. | Risk Codes | 11-23/24/25-39/23/24/25-20/21/22 |
| Molecular Structure |
|
Hazard Symbols | F,T |
| Synonyms |
1-Propanone,2-(diethylamino)-1-phenyl-, hydrochloride (9CI); Propiophenone,2-(diethylamino)-, hydrochloride (6CI,8CI);1-Phenyl-2-(diethylamino)propanone-1 hydrochloride;2-(Diethylamino)propiophenone hydrochloride; Amfepramon hydrochloride;Amphepramonum hydrochloride; Anfamon; Anorex; Danylen; Diethylpropionhydrochloride; Diethylpropione hydrochloride; Dobesin; Fepranon; Frekentine;Keramik; Keramin; Moderatan; Modulor; Parabolin; Phepranon; Prefamone; Regenon;Regenon hydrochloride; Tenuate; Tenuate hydrochloride; Tenuate-Dospan; Tepanil;Tylinal; a-(Diethylamino)propiophenonehydrochloride; a-Benzoyltriethylaminehydrochloride; a-Benzoyltriethylammoniumchloride |
Amfepramone hydrochloride Chemical Properties
Chemistry informtion about 2-Diethylaminopropiophenone Hydrochloride (CAS NO.134-80-5) is:
IUPAC Name: 2-(Diethylamino)-1-Phenylpropan-1-One Hydrochloride
Synonyms: Diethylpropion Hydrochloride ; 2-(Diethylamino)Propiophenone Hydrochloride ; 1-Phenyl-2-Diethylamino-1-Propanonehydrochloride ; 1-Phenyl-2-Diethylaminopropanone-1hydrochloride ; 2-(Diethylamino)-1-Phenyl-1-Propanonhydrochloride ; 2-(Diethylamino)-Propiophenonhydrochloride ; Alpha-Benzoyltriethylaminehydrochloride ; Alpha-Benzoyltriethylammoniumchloride
Product Categories: Aromatics ; Intermediates & Fine Chemicals ; Pharmaceuticals
MF: C13H20ClNO
MW: 241.76
EINECS: 205-156-5
Melting Point: 180-1810°C
Flash Point: 95.4 °C
Boiling Point: 292 °C at 760 mmHg
Vapour Pressure: 0.00189 mmHg at 25°C
Enthalpy of Vaporization: 53.14 kJ/mol
Following is the molecular structure of 2-Diethylaminopropiophenone Hydrochloride (CAS NO.134-80-5) is:
Amfepramone hydrochloride Uses
2-Diethylaminopropiophenone Hydrochloride (CAS NO.134-80-5) can be used to controlled substance (stimulant) and used as anorexic.
Amfepramone hydrochloride Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 160mg/kg (160mg/kg) | Therapie. Vol. 17, Pg. 373, 1962. | |
| mouse | LD50 | intravenous | 50mg/kg (50mg/kg) | Acta Pharmacologica et Toxicologica. Vol. 17, Pg. 182, 1960. | |
| mouse | LD50 | oral | 385mg/kg (385mg/kg) | Therapie. Vol. 17, Pg. 373, 1962. | |
| mouse | LD50 | subcutaneous | 450mg/kg (450mg/kg) | sense organs and special senses: mydriasis (pupillary dilation): eye behavioral: excitement skin and appendages (skin): hair: other | Acta Pharmaceutica Suecica. Vol. 4, Pg. 37, 1967. |
| rat | LD50 | intraperitoneal | 139mg/kg (139mg/kg) | behavioral: excitement | Acta Pharmacologica et Toxicologica. Vol. 17, Pg. 121, 1960. |
| rat | LD50 | oral | 400mg/kg (400mg/kg) | Therapie. Vol. 17, Pg. 373, 1962. |
Amfepramone hydrochloride Safety Profile
Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits very toxic fumes of HCl, NH3, and NOx.
Amfepramone hydrochloride Specification
2-Diethylaminopropiophenone Hydrochloride (CAS NO.134-80-5) is a off-white solid.
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