- Name
3'-Aminoacetanilide
- EINECS203-021-5
- CAS No.
102-28-3
- Density1.203 g/cm3
- PSA55.12000
- LogP1.88140
- Solubility1-5 g/100 mL at 24 °C in water
- Melting Point86-88 °C(lit.)
- FormulaC8H10N2O
- Boiling Point388.9 °C at 760 mmHg
- Molecular Weight150.18
- Flash Point189 °C
- Transport InformationN/A
- AppearanceGray solid.
- Safety26-36-37/39
- Risk Codes36/37/38
- Molecular Structure
- Hazard Symbols
Xi
- SynonymsXi
- Article Data39
3'-Aminoacetanilide Synthetic route
Conditions
| Conditions | Yield |
|---|
| With iron(III)-acetylacetonate; hydrazine hydrate In methanol at 150℃; Microwave irradiation; Green chemistry; | 99% |
Conditions| Conditions | Yield |
|---|
| With 1,4-diaza-bicyclo[2.2.2]octane at 65 - 90℃; for 6h; Time; Inert atmosphere; | 98.4% |
Conditions| Conditions | Yield |
|---|
| With sodium tetrahydroborate; TPGS-750-M In tetrahydrofuran; water at 20℃; for 0.5h; | 98% |
| With aluminum amalgam; water In tetrahydrofuran at 20℃; for 0.5h; | 96% |
| With iron; acetic acid In neat liquid at 50℃; for 0.25h; | 91% |
Conditions| Conditions | Yield |
|---|
| With chlorosulfonic acid In toluene at 90℃; for 0.5h; Beckmann rearrangement; | 98% |
| With tricarallylic acid at 160℃; for 0.0833333h; Beckmann rearrangement; Inert atmosphere; neat (no solvent); | 90% |
Conditions| Conditions | Yield |
|---|
| With dicyclohexyl(2',4',6'-triisopropyl-5-methoxy-3,4,6-trimethyl-[1,1'-biphenyl]-2-yl)phosphine; C50H70NO4PPdS; C50H70NO4PPdS; dicyclohexyl(2',4',6'-triisopropyl-4-methoxy-3,5,6-trimethyl-[1,1'-biphenyl]-2-yl)phosphine; ammonia; sodium t-butanolate In 1,4-dioxane at 80℃; for 24h; Inert atmosphere; | 48% |
Conditions| Conditions | Yield |
|---|
| In tetrahydrofuran at -10℃; for 5h; | 34.2% |
- 615-28-1
o-phenylenediamine dihydrochloride
Conditions| Conditions | Yield |
|---|
| With water das Hydrochlorid entsteht; | |
Conditions| Conditions | Yield |
|---|
| With hydrogenchloride das Hydrochlorid entsteht; ueber mehrere Stufen; | |
- 621-35-2
N-(3-aminophenyl)-acetamide hydrochloride
Conditions| Conditions | Yield |
|---|
| With sodium chloride pH ; | |
3'-Aminoacetanilide Chemical Properties
Product Name:N1-(3-Aminophenyl)acetamide
The MF of N1-(3-Aminophenyl)acetamide(102-28-3) is C8H10N2O.
The MW of N1-(3-Aminophenyl)acetamide(102-28-3) is 150.18.
Synonyms: N-ACETYL-M-PHENYLENEDIAMINE;N-ACETYL-1,3-PHENYLENEDIAMINE;N1-(3-AMINOPHENYL)ACETAMIDE;3’-amino-acetanilid;3-acetylaminoaniline
EINECS: 203-021-5
Product Categories: Intermediates of Dyes and Pigments;AMINEPRIMARY;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
Mol File: 102-28-3.mol
mp:86-88 °C(lit.)
Surface Tension of it is 53 dyne/cm and the density is 1.203 g/cm3
Flash Point: 189 °C
Enthalpy of Vaporization: 63.82 kJ/mol
Boiling Point: 388.9 °C at 760 mmHg
Water Solubility: 1-5 g/100 mL at 24 oC
CAS DataBase Reference:102-28-3(CAS DataBase Reference)
EPA Substance Registry:System 102-28-3(EPA Substance)
3'-Aminoacetanilide Uses
The N1-(3-Aminophenyl)acetamide(102-28-3) is used primarily as a reaction intermediate for dyes and disperse dyes
3'-Aminoacetanilide Toxicity Data With Reference
| 1. | | eye-rbt 500 mg/24H SEV | | 28ZPAK Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku Marhold, J.V.,Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha,Czechoslovakia.: 1972,129. |
| 2. | | mmo-sat 333 µg/plate | | EMMUEG Environmental and Molecular Mutagenesis. 11 (Suppl 12)(1988),1. |
| 3. | | ivn-mus LD50:320 mg/kg | | CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) NX#02899 . |
3'-Aminoacetanilide Consensus Reports
Reported in EPA TSCA Inventory.
3'-Aminoacetanilide Safety Profile
Poison by intravenous route. Moderately toxic by ingestion. A severe eye irritant. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes:
Xi
Risk Statements:36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin ;
Safety Statements:26-36-37/39
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice ;
S36:Wear suitable protective clothing ;
S37/39:Wear suitable gloves and eye/face protection ;
WGK Germany:3
RTECS:AD8050000
3'-Aminoacetanilide Specification
It is Incompatible with Strong oxidizing agents, acids, acetic anhydride, acid chlorides, carbon dioxide.Hazardous Decomposition Products is Nitrogen oxides, carbon monoxide, carbon dioxide.
