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2,4-Pyridinedicarboxylic acid

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Name

2,4-Pyridinedicarboxylic acid

EINECS 207-892-2
CAS No. 499-80-9 Density 1.551 g/cm3
PSA 87.49000 LogP 0.47800
Solubility Soluble in water at 20°C 4.5 g/L. Melting Point 243-246 °C
Formula C7H5NO4 Boiling Point 574.8 °C at 760 mmHg
Molecular Weight 167.121 Flash Point 301.4 °C
Transport Information N/A Appearance white to off-white crystalline powder
Safety 24/25-26 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 499-80-9 (2,4-Pyridinedicarboxylic acid) Hazard Symbols IrritantXi
Synonyms

2,4-Dicarboxylpyridine;2,4-Lutidinic acid;Lutidinic acid;NSC 403248;

Article Data 23

2,4-Pyridinedicarboxylic acid Synthetic route

108-47-4

2,4-lutidine

499-80-9

pyridine-2,4-dicarboxylic acid

Conditions
ConditionsYield
With 18-crown-6 ether; potassium tert-butylate; oxygen In 1,2-dimethoxyethane at 60℃; under 3800 Torr; for 48h;52%
With potassium permanganate
With permanganate(VII) ion
2150-18-7

2-ethyl-4-methylpyridine

499-80-9

pyridine-2,4-dicarboxylic acid

Conditions
ConditionsYield
With permanganate(VII) ion
536-88-9

4-ethyl-2-methyl-pyridine

499-80-9

pyridine-2,4-dicarboxylic acid

Conditions
ConditionsYield
With permanganate(VII) ion
2.2'-dimethyl-dipyridyl-(4.4')

2.2'-dimethyl-dipyridyl-(4.4')

499-80-9

pyridine-2,4-dicarboxylic acid

Conditions
ConditionsYield
With permanganate(VII) ion
2-methyl-pyridine-carboxylic acid-(4)

2-methyl-pyridine-carboxylic acid-(4)

499-80-9

pyridine-2,4-dicarboxylic acid

Conditions
ConditionsYield
With alkaline permanganate solution
crude lutidine

crude lutidine

499-80-9

pyridine-2,4-dicarboxylic acid

Conditions
ConditionsYield
With permanganate(VII) ion
108-47-4

2,4-lutidine

7664-93-9

sulfuric acid

selenium

selenium

A

4021-11-8

2-methylisonicotinic acid

B

499-80-9

pyridine-2,4-dicarboxylic acid

Conditions
ConditionsYield
at 300℃;
54089-05-3

2-carbamoyl-4-cyanopyridine

499-80-9

pyridine-2,4-dicarboxylic acid

Conditions
ConditionsYield
With sodium hydroxide In water
121-34-6

3-methoxy-4-hydroxybenzoic acid

499-80-9

pyridine-2,4-dicarboxylic acid

Conditions
ConditionsYield
With thiostrepton; ammonium chloride at 30℃; for 168h;
With disodium hydrogenphosphate; potassium dihydrogenphosphate; chloramphenicol; magnesium sulfate; ammonium chloride; thiostrepton A; sodium chloride; calcium chloride In water at 30℃; for 168h; Reagent/catalyst; Enzymatic reaction;
lignocellulose

lignocellulose

499-80-9

pyridine-2,4-dicarboxylic acid

Conditions
ConditionsYield
With thiostrepton; ammonium chloride at 30℃; for 168h; Time;

2,4-Pyridinedicarboxylic acid Specification

The 2,4-Pyridinedicarboxylic acid, with the CAS registry number 499-80-9, is also known as Lutidinic acid. Its EINECS registry number is 207-892-2. This chemical's molecular formula is C7H5NO4 and molecular weight is 167.12. What's more, both its IUPAC name and systematic name are the same which is called Pyridine-2,4-dicarboxylic acid. It is used as organic synthetic reagent.

Physical properties about 2,4-Pyridinedicarboxylic acid are: (1)ACD/LogP: -0.20; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -3.84; (4)ACD/LogD (pH 7.4): -4.34; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 5; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 65.49 Å2; (13)Index of Refraction: 1.627; (14)Molar Refractivity: 38.2 cm3; (15)Molar Volume: 107.7 cm3; (16)Surface Tension: 83.5 dyne/cm; (17)Density: 1.551 g/cm3; (18)Flash Point: 301.4 °C; (19)Enthalpy of Vaporization: 90.58 kJ/mol; (20)Boiling Point: 574.8 °C at 760 mmHg; (21)Vapour Pressure: 4.71E-14 mmHg at 25 °C.

Preparation of 2,4-Pyridinedicarboxylic acid: this chemical can be prepared by 2,4-Dimethyl-pyridine. This reaction needs reagents oxygen, Cu(NO3)2, H2O at temperature of 225-230 °C.

2,4-Pyridinedicarboxylic acid can be prepared by 2,4-Dimethyl-pyridine.

When you are dealing with this chemical, you should be very careful. This chemical is inflammation to the skin, eyes and respiratory system or other mucous membranes. Therefore, you should avoid contacting with skin and eyes. In case of contacting with eyes, you should rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1) SMILES: O=C(O)c1nccc(C(=O)O)c1
(2) InChI: InChI=1S/C7H5NO4/c9-6(10)4-1-2-8-5(3-4)7(11)12/h1-3H,(H,9,10)(H,11,12)
(3) InChIKey: MJIVRKPEXXHNJT-UHFFFAOYSA-N

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