Original ArticleCiprofloxacin plus erythromycin or Ambroxol (cas 18683-91-5) ameliorates endotracheal tube-associated Pseudomonas aeruginosa biofilms in a rat model
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Add time:09/28/2019 Source:sciencedirect.com
Background and objectivePseudomonas aeruginosa is a multi-drug resistant bacterium, with its biofilm-growing mucoid (alginate-producing) strains being particularly resistant. As atomized drug administration is a common practice in pediatric patients, we compared the effect of inhalational therapy with erythromycin plus ciprofloxacin, with that of Ambroxol (cas 18683-91-5) plus ciprofloxacin, against biofilm producing strains of P. aeruginosa.
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