USD $20.00-30.00 / Gram
USD $10.00-20.00 / Gram
USD $49.50-54.20 / Gram
USD $15.00-50.00 / Kilogram
USD $2.00-10.00 / Kilogram
USD $9.00-99.00 / Kilogram
USD $100.00-150.00 / Kilogram
USD $9.00-99.00 / Kilogram
USD $2.00-10.00 / Kilogram
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1.noble metal catalysts (pt.pd...)
2.organic phosphine ligands (tert-butyl-phosphine.cyclohexyl-phosphine...)
3.oled intermediates (fluorene,carbazole,boric acid...)
4.customs synthesis
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fosaprepitant dimeglumine basic information |
product name: | fosaprepitant dimeglumine |
synonyms: | phosphonic acid, (3-(((2r,3s)-2-((1r)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-morpholinyl)methyl)-2,5-dihydro-5-oxo-1h-1,2,4-triazol-1-yl)-, compd. with 1-deoxy-1-(methylamino)-d-glucitol (1:2);unii-d35fm8t64x;[3-[[(2r,3s)-2-[(1r)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1h-1,2,4-triazol-1-yl]phosphonate 1-deoxy-1-(methylamino)-d-glucitol;1-deoxy-1-(methylamino)-d-glucitol [3-[[(2r,3s)-2-[(1r)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1h-1,2,4-triazol-1-yl]phosphonate;1-deoxy-1-(methylamino)-d-glucitol [[(2r,3s]-2-[(1r)-1-[3,5-bis (trifluoromethyl)phenyl] phenyl]ethoxy]-(4-fluorophenyl);fosaprepitant dimeglumine salt;3-[2(r)-[1(r)-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3(s)-(4-fluorophenyl)morpholin-4-ylmethyl]-5-oxo-4,5-dihydro-1h-1,2,4-triazole-1-phosphinic acid bis(n-methyl-d-glucamine) salt;fosaprepitant dimeglumine, >=99% |
cas: | 265121-04-8 |
mf: | c60h78f14n10o20p2 |
mw: | 1587.2414868 |
einecs: | |
product categories: | other apis;inhibitors |
mol file: | 265121-04-8.mol |
fosaprepitant dimeglumine chemical properties |
safety information |
fosaprepitant dimeglumine usage and synthesis |
uses | fosaprepitant is a water-soluble phosphoryl prodrug for aprepitant which is a nk1 antagonist |
definition | chebi: an organoammonium salt obtained by reaction of fosaprepitant with two equivalents of 1-deoxy-1-(methylamino)-d-glucitol. a substance p/neurokinin 1 (nk1) receptor antagonist. aprepitant is a selective high-affinity antagonist of human subs ance p/neurokinin 1 (nk1) receptors. aprepitant has little or no affinity for serotonin (5-ht3), dopamine, and corticosteroid receptors, the targets of existing therapies for chemotherapy-induced nausea and vomiting and postoperative nausea and vomiting |