98603-84-0

Basic information

• Product Name: SIALYL LEWIS X
• Synonyms: 5-ACETAMIDO-3,5-DI-DEOXY-D-GLYCERO-ALPHA-D-GALACTO-2-NOULOPYRANOSYL(2-3)-BETA-D-GALACTOPYRANOSYL(1-4)-[ALPHA-L-FUCOPYRANOSYL(1-4)]-2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSIDE;3'-SIALYL LEWIS;3'-SIALYL-LEWISX;3'-SIALYL-LEWIS-X TETRASACCHARIDE;NEU5AC-ALPHA2,3GAL-BETA1,4(FUC-ALPHA1,3)GLCNAC;NEU5AC-ALPHA2,3GALBETA1,4(FUCALPHA1,3)GLCNAC, SODIUM SALT;NEUNAC-ALPHA2-3GAL-BETA1-4(FUC-ALPHA1-3)GLCNAC;NEU5AC2-A-3GAL1-B-4[FUC1-A-3]GLCNAC
• CAS NO: 98603-84-0
• Molecular Formula: C31H52N2O23
• Molecular Weight: 820.74
• Product Categories: Oligosaccharide Compounds;Oligosaccharides
• Mol File: 98603-84-0.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 1285.8°Cat760mmHg
• Flash Point: 731.4°C
• Appearance: /
• Density: 1.66g/cm³
• Storage Temp.: −20°C
• Solubility: Methanol (Slightly), Water (Slightly)
• Stability: Store in freezer
• CAS DataBase Reference: SIALYL LEWIS X(CAS DataBase Reference)
• NIST Chemistry Reference: SIALYL LEWIS X(98603-84-0)
• EPA Substance Registry System: SIALYL LEWIS X(98603-84-0)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 98603-84-0(Hazardous Substances Data)

Usage

Description

SIALYL LEWIS X is a carbohydrate antigen that is involved in various biological processes, including cell adhesion, immune response, and cell-cell interactions. It is composed of a sialic acid residue linked to a Lewis X structure, which is a trisaccharide composed of fucose, galactose, and glucose. SIALYL LEWIS X plays a crucial role in the binding to endothelial adhesion molecule E-selectin and is implicated in colon cancer cell adhesion.

Uses

Used in Biomedical Research:
SIALYL LEWIS X is used as an antigen that binds to the endothelial adhesion molecule E-selectin. This interaction is important in various biological processes, including leukocyte recruitment during inflammation and immune response.
Used in Cancer Research:
SIALYL LEWIS X is used as an E-selectin ligand, which is implicated in colon cancer cell adhesion. The binding of SIALYL LEWIS X to E-selectin on the surface of colon cancer cells helps them adhere to the endothelium, facilitating their extravasation and metastasis.
Used in Drug Development:
SIALYL LEWIS X can be used as a target for drug development, as modulating its interaction with E-selectin may have therapeutic potential in treating various diseases, including cancer and inflammatory disorders.
Used in Diagnostics:
SIALYL LEWIS X can be used as a biomarker for certain diseases, as its presence on the surface of cells may indicate abnormal cell behavior or the presence of disease.
Overall, SIALYL LEWIS X is a versatile molecule with various applications in biomedical research, cancer research, drug development, and diagnostics. Its role in cell adhesion and immune response makes it an important target for further investigation and potential therapeutic intervention.

Biochem/physiol Actions

Antigen which binds to endothelial adhesion molecule, E-selectin.