98149-13-4 Usage
Description
17β-Cyanmethyl-4-brom-17β-hydroxy-oestra-4,9-dien-3-on, also known as (17α)-4-Bromo-17-hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile, is an impurity of Dienogest (D441870), a synthetic steroidal progestin used as a contraceptive agent. It is a derivative of the estratriene family, characterized by the presence of a bromo group at the 4-position, a cyano group at the 17β-methyl position, and a hydroxyl group at the 17β position.
Uses
Used in Pharmaceutical Industry:
17β-Cyanmethyl-4-brom-17β-hydroxy-oestra-4,9-dien-3-on is used as an impurity in Dienogest, a contraceptive agent. It is important to monitor and control the levels of this impurity to ensure the safety, efficacy, and quality of the final pharmaceutical product.
Check Digit Verification of cas no
The CAS Registry Mumber 98149-13-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,1,4 and 9 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 98149-13:
(7*9)+(6*8)+(5*1)+(4*4)+(3*9)+(2*1)+(1*3)=164
164 % 10 = 4
So 98149-13-4 is a valid CAS Registry Number.
98149-13-4Relevant articles and documents
Investigations on the Bromination/Dehydrobromination of 17α-Cyanomethyl-17β-hydroxy-estr-5(10)-en-3-one
Menzenbach, B.,Huebner, M.,Ponsold, K.
, p. 893 - 898 (2007/10/02)
Bromination/dehydrobromination of 17α-cyanomethyl-17β-hydroxy-estr-5(10)-en-3-one 1a in the presence of pyridine leads to 17α-cyanomethyl-17β-hydroxy-estra-4,9-dien-3-one 2a.The reaction was studied in various solvents with several bromination agents.Intermediates and byproducts of the reaction were isolated and their structures elucidated.
