97227-32-2 Usage
Description
MONO-2-O-(P-TOLUENESULFONYL)-GAMMA-CYCLODEXTRIN is a modified cyclodextrin that has a p-toluenesulfonyl group attached to the 2-O position of the gamma-cyclodextrin molecule. This modification enhances the solubility and stability of the cyclodextrin, making it suitable for various applications in different industries.
Uses
Used in Pharmaceutical Industry:
MONO-2-O-(P-TOLUENESULFONYL)-GAMMA-CYCLODEXTRIN is used as a pharmaceutical excipient for enhancing the solubility and bioavailability of poorly water-soluble drugs. Its unique structure allows it to form inclusion complexes with various drug molecules, improving their dissolution and absorption in the body.
Used in Chemical Synthesis:
In the field of chemical synthesis, MONO-2-O-(P-TOLUENESULFONYL)-GAMMA-CYCLODEXTRIN serves as a versatile building block for the preparation of alkylamine-modified cyclodextrins. These modified cyclodextrins have potential applications in the inhibition of quorum sensing in gram-negative bacteria, which can help control bacterial infections and biofilm formation.
Used in Analytical Chemistry:
MONO-2-O-(P-TOLUENESULFONYL)-GAMMA-CYCLODEXTRIN is also utilized in analytical chemistry as a chiral selector for the separation and analysis of enantiomers. Its ability to form inclusion complexes with chiral molecules allows for the efficient separation of enantiomers, which is crucial in the development and quality control of chiral drugs.
Used in Food Industry:
In the food industry, MONO-2-O-(P-TOLUENESULFONYL)-GAMMA-CYCLODEXTRIN is employed as a flavor and fragrance encapsulation agent. Its ability to form inclusion complexes with volatile compounds helps to protect and stabilize flavors and fragrances, enhancing their shelf life and performance in various food products.
Used in Cosmetics Industry:
In the cosmetics industry, MONO-2-O-(P-TOLUENESULFONYL)-GAMMA-CYCLODEXTRIN is used as a stabilizing and solubilizing agent for various cosmetic ingredients. Its ability to form inclusion complexes with active ingredients helps to improve their solubility, stability, and bioavailability in cosmetic formulations, enhancing their efficacy and performance.
Check Digit Verification of cas no
The CAS Registry Mumber 97227-32-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,7,2,2 and 7 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 97227-32:
(7*9)+(6*7)+(5*2)+(4*2)+(3*7)+(2*3)+(1*2)=152
152 % 10 = 2
So 97227-32-2 is a valid CAS Registry Number.
97227-32-2Relevant articles and documents
Synthesis of C6A-to-C6A and C3A-to-C3A diamide linked γ-cyclodextrin dimers
Pham, Duc-Truc,Ngo, Huy Tien,Lincoln, Stephen F.,May, Bruce L.,Easton, Christopher J.
, p. 2895 - 2898 (2010)
The syntheses of three new diamide-linked γ-cyclodextrin dimers joined by substitution at either a glucopyranose C6A or C3A carbon are reported. The syntheses involve the reaction of either C6A or C3A amino-substituted γ-cyclodextrin with bis(4-nitrophenyl)succinate to form succinamide linked γ-cyclodextrin dimers or reaction of C6A azide-substituted γ-cyclodextrin with carbon dioxide to form a urea linked γ-cyclodextrin dimer.
Efficient regioselective functionalizations of cyclodextrins carried out under microwaves or power ultrasound
Martina, Katia,Trotta, Francesco,Robaldo, Bruna,Belliardi, Nikka,Jicsinszky, László,Cravotto, Giancarlo
, p. 9185 - 9189 (2008/09/18)
Regioselective syntheses of differently functionalized cyclodextrins (CDs) were efficiently carried out under ultrasound or microwave irradiation. 6I-Deoxy-6I-thio-β-CD, 6I-deoxy-6I-formyl-β-CD, and 6A,6D-dideoxy-6A,6D-dithio-β-CD were prepared under microwave irradiation. A new rapid and efficient ultrasound-assisted protocol is described for the synthesis of 3I-azido-3I-deoxy-α, -β, and -γ-CD by selective tosylation followed by azide substitution.
