97206-05-8

Basic information

• Product Name: Benzenebutanoic acid, b-[[(phenylmethoxy)carbonyl]amino]-, methyl ester, (S)-
• CAS NO: 97206-05-8
• Molecular Formula: C19H21NO4
• Molecular Weight: 327.38
• Mol File: 97206-05-8.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Benzenebutanoic acid, b-[[(phenylmethoxy)carbonyl]amino]-, methyl ester, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenebutanoic acid, b-[[(phenylmethoxy)carbonyl]amino]-, methyl ester, (S)-(97206-05-8)
• EPA Substance Registry System: Benzenebutanoic acid, b-[[(phenylmethoxy)carbonyl]amino]-, methyl ester, (S)-(97206-05-8)

Safety Data

• Hazardous Substances Data: 97206-05-8(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 15196-02-8 (S)-3-[(benzyloxycarbonyl)amino]-1-diazo-4-phenyl-2-butanone 
• 172695-21-5 (S)-2-(N-benzyloxyacarbonylamino)-3-phenylpropyl cyanide 
• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 501-53-1 benzyl chloroformate 
• 63-91-2 L-phenylalanine 
• 532-31-0 silver benzoate 
• 109453-49-8 (C₈H₇O₂)(NHCHCOO)(CH₂C₆H₅)(CO₂C₂H₅) 
• 186581-53-3 diazomethane 
• 26250-86-2 (S)-3-benzyloxycarbonylamino-4-phenylbutyric acid 
• 1161-13-3 N-Cbz-L-Phe 
• 154484-05-6 (S)-2-benzyloxycarbonylamino-1-iodo-3-phenylpropane 
• 6372-14-1 N-((benzyloxy)carbonyl)-L-phenylalaninol 
• 3182-95-4 L-Phenylalaninol 

Downstream Products

• 200267-80-7 (S)-benzyl 4-hydroxy-1-phenylbutan-2-ylcarbamate 
• 1616868-38-2 (S)-3-(benzyloxycarbonylamino)-4-phenylbutyl methanesulfonate 
• 63328-06-3 (4R)-4-amino-5-phenylpentanoic acid 
• 15099-85-1 β-homo-(S)-phenylalanine 
• 65985-78-6 (S)-N-<1-Benzyl-4-diazo-3-oxo-butyl>-carbaminsaeure-benzylester 
• 65985-80-0 (R)-4-Benzyloxycarbonylamino-5-phenyl-valeriansaeure-methylester 
• 65985-82-2 (R)-4-Benzyloxycarbonylamino-5-phenyl-valeriansaeure 
• 65985-79-7 (S)-N-<1-Benzyl-4-chlor-3-oxo-butyl>-carbaminsaeure-benzylester 
• 868670-42-2 ((S)-1-Benzyl-3-oxo-propyl)-carbamic acid benzyl ester 
• 126015-23-4 (2S,3S)-3-[[(benzyloxy)carbonyl]amino]-2-hydroxy-4-phenylbutanoic acid methyl ester 
• 126015-22-3 (2R,3S)-3-[[(benzyloxy)carbonyl]amino]-2-hydroxy-4-phenylbutanoic acid methyl ester 
• 170116-36-6 Methyl (2S,3S)-3-(benzyloxycarbonylamino)-2-methyl-4-phenylbutanoate 
• 68978-89-2 homo-β-phenylalanine methyl ester 

Relevant articles and documents

Synthesis and evaluation of chirally defined side chain variants of 7-chloro-4-aminoquinoline to overcome drug resistance in malaria chemotherapy

A novel 4-aminoquinoline derivative [(S)-7-chloro-N-(4-methyl-1-(4-methyl-piperazin-1-yl)pentan-2-yl)-quinolin-4-amine triphosphate] exhibiting curative activity against chloroquine-resistant malaria parasites has been identified for preclinical development as a blood schizonticidal agent. The lead molecule selected after detailed structure-activity relationship (SAR) studies has good solid-state properties and promising activity against in vitro and in vivo experimental malaria models. The in vitro absorption, distribution, metabolism, and excretion (ADME) parameters indicate a favorable drug-like profile.

Synthesis of enantiopure free and N-benzyloxycarbonyl-protected 3-substituted homotaurines from naturally occurring amino acids

Enantiopure N-benzyloxycarbonyl-protected and free 3-substituted homotaurines were synthesized from naturally occurring amino acids via N-benzyloxycarbonyl protection, Arndt-Eistert homologation, reduction, esterification with thioacetic acid, and oxidation with performic acid. The current method is a convenient, practical, and salt-free method for the synthesis of enantiopure 3-substituted homotaurine with moderate to good yields.

A convenient preparation of (2SR,3S)-3-amino-2-hydroxy-4-phenylbutanoic acid; an important peptide bond isostere

We present an efficient synthesis of N-Z-(2SR,3S)-3-amino-2-hydroxy-4- phenylbutanoic acids by hydroxylation of an enolate derived from methyl (3S)N-Z-3-amino-4-phenylbutanoate with oxodiperoxymolybdenum (pyridine) (hexamethyl phosphoric triamide) complex