96-45-7 Usage
Description
Ethylenethiourea, a thiourea derivative, is a rubber chemical that has been known to cause contact dermatitis primarily in rubber workers.
Uses
Used in Rubber Industry:
Ethylenethiourea is used as an accelerator in the curing of polychloroprene (neoprene) and polyacrylate rubber. It enhances the vulcanization process, which is essential for the production of rubber products with desired properties.
Used in Industrial Applications:
Ethylenethiourea is used in the production of mechanical and automotive products, wire and cable production, construction, and adhesives, where neoprene rubbers are utilized.
Used in Automotive and Aircraft Applications:
Polyacrylate rubbers, which are vulcanized using ethylenethiourea, are used in the manufacturing of seals, O-rings, and gaskets for automotive and aircraft applications.
Used in Pesticide Production:
Ethylenethiourea is used in the manufacture of ethylene-bisdithiocarbamate pesticides, such as Maneb, Mancozeb, Metiram, and Zineb, which are important for agricultural applications.
Used in Electroplating Baths:
Ethylenethiourea serves as an intermediate in various chemical processes, including its use in electroplating baths.
Used in Antioxidant Production:
It is also used as an intermediate in the production of antioxidants, which are crucial in various industries to prevent oxidation and degradation of materials.
Used in Dyes, Pharmaceuticals, and Synthetic Resins:
Ethylenethiourea finds application in the production of dyes, pharmaceuticals, and synthetic resins, although there is no evidence of its commercial use for these purposes.
Used in MRI Studies:
2-Imidazolidinethione, a derivative of ethylenethiourea, is used as a new contrast agent for MRI studies based on proton chemical exchange dependent saturation transfer.
Used as a Corrosion Inhibitor:
2-Imidazolidinethione also functions as a corrosion inhibitor due to the adsorption of its molecular species, providing protection against corrosion in various applications.
Air & Water Reactions
Slightly soluble in water.
Reactivity Profile
Ethlenethiourea may be sensitive to prolonged exposure to light. Incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials generate heat and in many cases hydrogen gas. May react with acids to liberate hydrogen sulfide.
Hazard
Questionable carcinogen.
Health Hazard
Ethylene thiourea (ETU) is an
antithyroid substance and animal carcinogen.
Fire Hazard
Ethylene thiourea is combustible.
Flammability and Explosibility
Nonflammable
Contact allergens
Ethylene thiourea, a thiourea derivative, is a rubber chemical. It caused contact dermatitis mainly in rubber workers.
Potential Exposure
Ethylene thiourea is used extensively
as an accelerator in the curing of polychloroprene
(Neoprene) and other elastomers; as a vulcanizing accelerator in rubber processing; in electroplating baths. In addition, exposure to ethylene thiourea also results from the
very widely used ethylene bisdithiocarbamate fungicides.
Ethylene thiourea may be present as a contaminant in the
ethylene bisdithiocarbamate fungicides and can also be
formed when food containing the fungicides is cooked
Carcinogenicity
Ethylene thiourea is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
Purification Methods
Crystallise it from EtOH or amyl alcohol. [Beilstein 24 III/IV 22.]
Incompatibilities
Incompatible with oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates, chlorine,
bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases,
strong acids, oxoacids, epoxides, acid anhydrides, and
acrolein
Waste Disposal
Incineration in a furnace
equipped with afterburner and scrubber.
Check Digit Verification of cas no
The CAS Registry Mumber 96-45-7 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 9 and 6 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 96-45:
(4*9)+(3*6)+(2*4)+(1*5)=67
67 % 10 = 7
So 96-45-7 is a valid CAS Registry Number.
InChI:InChI=1/C3H6N2S/c6-5-2-1-4-3-5/h3,6H,1-2H2
96-45-7Relevant articles and documents
Solar-light driven photocatalytic conversion of p-nitrophenol to p-aminophenol on CdS nanosheets and nanorods
Khan, Azam,Rehman, Zia-ur-,Khan, Abdullah,Ambareen, Hina,Ullah, Haseeb,Abbas, Syed Mustansar,Khan, Yaqoob,Khan, Rajwali
, p. 99 - 103 (2017)
A simple synthetic protocol devoid of toxic surfactants was applied for the synthesis of CdS nanosheets and nanorods by thermolyzing bis(4-benzylpiperadine-1-carbodithioate-κ2 S, S′) cadmium(II) (1) and propane-1,3-diyl bis (piperidincarbamodithioate)cadmium(II) (2) using ethylenediamine (en) as a solvent. The as obtained products were characterized by TEM, PXRD, and UV–Visible spectroscopy. The nanosheets (1) and nanorods (2) were confirmed by HR-TEM with a lattice spacing of 0.33?nm which corresponds to the 002 plane of hexagonal CdS, observations in consonance with XRD. Based upon the band gap obtained from UV–Vis, 2.91?eV (nanosheets) and 2.65?eV (nanorods), these nanoparticles (NPs) were used as solar light driven photocatalyst for the conversion of p-nitrophenol to p-aminophenol. The nanorods (8?min) were found slightly more efficient than nanosheets (10?min), and the conversion efficiency of both remained above 92% even after 3rd cycle without any structural damage as revealed by the afterward PXRD. The better catalytic activity of both morphologies can be attributed to quantum size effect and good optical absorbance.
Synthesis method of heterocyclic compound containing bis (trimethylsilyl)
-
Paragraph 0047; 0052-0053; 0056; 0061-0062; 0071; 0073; ..., (2021/09/29)
The method comprises the following steps: first adopting bis (trichloromethyl) carbonate, ethylenediamine, an aqueous sodium hydroxide solution, chloroform and a supported catalyst to obtain 2 - imidazolidinone. Or, ethylenediamine, ethanol, distilled water, a supported catalyst, carbon disulfide and hydrochloric acid are prepared to obtain ethylene thiourea. The trimethylchlorosilane is dissolved in an organic solvent, ammonia gas is introduced, and heated to reflux until no white precipitate is generated and filtered to obtain the filtrate. The raw material 2 - imidazolidinone or ethylidene thiourea is then dissolved to obtain the raw material solution, ammonium sulfate is added, and the filtrate is added dropwise, heated and refluxed 5 - 6h, cooled to room temperature, filtered, and the product is obtained. The molar ratio of the raw material to the trimethyl chlorosilane is 1: (2.1 - 2.5), the quality of ammonium sulfate is 1.5 - 2% of the raw material. The preparation method is simple and high in yield.
Bis-(triethylphosphine)platinum(II) complexes with thiones as anti cancer agents
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Page/Page column 20, (2017/02/28)
Platinum(II) complexes having mixed ligands as anticancer agents. The central platinum atom is coordinated by two phosphine ligands and two heterocyclic thione ligands. Each heterocyclic thione ligand has a five-, six- or seven-membered heterocyclic ring with two nitrogen atoms at positions 1 and 3 of the ring and a thiocarbonyl group at position 2. Pharmaceutical compositions incorporated the platinum(II) complexes, methods of synthesizing the complexes and methods of treating cancers with the complexes or pharmaceutical compositions thereof are also described.
A new imidazoline-containing Bunte salt: Synthesis, molecular and electronic structure
S?czewski, Franciszek,Gdaniec, Maria,Data, Krzysztof
, p. 359 - 363 (2017/10/25)
S-[(4,5-dihydro-1H-imidazol-2-yl)methyl]sulfothioate, a new imidazoline-containing Bunte salt 4 was prepared by reacting 2-chloromethylimidazoline 3 with sodium thiosulfate in aqueous solution at room temperature. The mechanism of the concerted SN2 reaction pathway was studied by means of quantum chemical calculations at the B3LYP/6-31G?? level of theory. The molecular structure of compound 4 incorporating a formal amidine moiety was confirmed by single crystal X-ray diffraction analysis, while its electronic structure was studied using quantum chemical calculations at the MP2/6-311++G?? level of theory.