959215-76-0Relevant articles and documents
NONCRUSHABLE PILL FORMULATIIONS
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Paragraph 00345-00346, (2018/07/29)
Non-crushable pill formulations and methods of using the formulations are disclosed. A non- crushable pill formulation for preventing unintended use of a drug, comprising a polymer, the polymer forming a polymer backbone of the complex; cross-linkers, the
Optimization of naltrexone diclofenac codrugs for sustained drug delivery across microneedle-treated skin
Ghosh, Priyanka,Lee, Domin,Kim, Kyung Bo,Stinchcomb, Audra L.
, p. 148 - 159 (2014/01/17)
Purpose: The purpose of this work was to optimize the structure of codrugs for extended delivery across microneedle treated skin. Naltrexone, the model compound was linked with diclofenac, a nonspecific cyclooxygenase inhibitor to enhance the pore lifetim