947412-10-4Relevant articles and documents
Target-Based Design of Promysalin Analogues Identifies a New Putative Binding Cleft in Succinate Dehydrogenase
Post, Savannah J.,Keohane, Colleen E.,Rossiter, Lauren M.,Kaplan, Anna R.,Khowsathit, Jittasak,Matuska, Katie,Karanicolas, John,Wuest, William M.
, p. 5697 - 5722 (2020)
Promysalin is a small-molecule natural product that specifically inhibits growth of the Gram-negative pathogen Pseudomonas aeruginosa (PA). This activity holds promise in the treatment of multidrug resistant infections found in immunocompromised patients