94226-56-9

Basic information

• Product Name: Glycine, N,N-bis(phenylMethyl)-, 1,1-diMethylethyl ester
• Synonyms: Glycine, N,N-bis(phenylMethyl)-, 1,1-diMethylethyl ester
• CAS NO: 94226-56-9
• Molecular Formula: C₂₀H₂₅NO₂
• Molecular Weight: 311.418
• Mol File: 94226-56-9.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Glycine, N,N-bis(phenylMethyl)-, 1,1-diMethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Glycine, N,N-bis(phenylMethyl)-, 1,1-diMethylethyl ester(94226-56-9)
• EPA Substance Registry System: Glycine, N,N-bis(phenylMethyl)-, 1,1-diMethylethyl ester(94226-56-9)

Safety Data

• Hazardous Substances Data: 94226-56-9(Hazardous Substances Data)

Upstream product

• 540-88-5 acetic acid tert-butyl ester 
• 52742-32-2 N,N-dibenzyl-O-benzoylhydroxylamine 
• 5292-43-3 bromoacetic acid tert-butyl ester 
• 103-49-1 dibenzylamine 

Downstream Products

• 129397-20-2 (2S,3R)-3-Butyl-2-dibenzylamino-pentanedioic acid 1-tert-butyl ester 5-ethyl ester 
• 129397-21-3 (2S,3R)-2-Dibenzylamino-3-heptyl-pentanedioic acid 1-tert-butyl ester 5-ethyl ester 
• 134532-13-1 N-δ-Boc-N-α-dibenzyl-3-hydroxy-DL-ornithine tert-butyl ester 
• 94226-59-2 2-Dibenzylamino-3-hydroxy-butyric acid tert-butyl ester 
• 94226-75-2 2-Dibenzylamino-3-hydroxy-4,4-dimethyl-pentanoic acid tert-butyl ester 
• 94226-75-2 (2R,3S)-2-Dibenzylamino-3-hydroxy-4,4-dimethyl-pentanoic acid tert-butyl ester 
• 94226-75-2 (2R,3R)-2-Dibenzylamino-3-hydroxy-4,4-dimethyl-pentanoic acid tert-butyl ester 
• 94226-78-5 2-Dibenzylamino-3-oxo-butyric acid tert-butyl ester 
• 956904-50-0 tert-butyl 2-dibenzylamino-4-chloro-3,3-dimethyl-4-(p-tolylsulfinyl)butanoate 
• 956904-52-2 tert-butyl 2-dibenzylamino-2-{1-[chloro(p-tolylsulfinyl)methyl]cyclohexyl}acetate 
• 7462-45-5 N,N-dibenzyl-DL-threonine 
• 94226-65-0 2-Dibenzylamino-3-hydroxy-nonanoic acid methyl ester 
• 94226-63-8 2-Dibenzylamino-3-hydroxy-3-phenyl-propionic acid tert-butyl ester 
• 7462-45-5 (2S,3S)-2-Dibenzylamino-3-hydroxy-butyric acid 

Relevant articles and documents

Selective α-amination and α-acylation of esters and amides via dual reactivity of O-acylhydroxylamines toward zinc enolates

Selective α-amination and α-acylation of esters and amides have been developed, employing O-acylhydroxylamines as a dually reactive aminating and acylating reagent. Treatment of zinc enolates with O-acylhydroxylamines provides solely 1,3-dicarbonyl compounds under mild conditions. Introduction of a copper catalyst into the system shifts the reactivity entirely, yielding α-amination products exclusively.

Chemoenzymatic synthesis of enantiomerically pure (2S,3R,4S)-4- hydroxyisoleucine, an insulinotropic amino acid isolated from fenugreek seeds

A short six-step synthesis of (2S,3R,4S)-4-hydroxyisoleucine (1a) with total control of stereochemistry is reported, the last step being the enzymatic resolution by hydrolysis of a N-phenylacetyl lactone derivative using the commercially available penicillin acylase G immobilized on Eupergit C (E-PAC). Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.

STEREOSELECTIVE SYNTHESIS OF t-BUTYL 2-AMINO-2,5-DIDEOXY-L-LYXO-PENTANOATE: FORMAL SYNTHESIS OF L-DAUNOSAMINE

Enantiomerically pure t-Butyl 2-amino-2,5-dideoxy-L-lyxo-pentanoate 4c is synthesized via the highly diastereoselective MgBr2 mediated addition of dibenzylamino acetate silylketene acetal 2 to O-benzyl lactic aldehyde 3.The synthesis of γ-lactone 5c, a known intermediate in the synthesis of L-daunosamine, is also described.