93993-77-2

Basic information

• Product Name: (2E)-1-(3,6-dihydroxy-2,4-dimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one
• Synonyms: 1-(3,6-Dihydroxy-2,4-dimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one; 3',6'-Dihydroxy-2',4,4'-trimethoxy-chalcone
• CAS NO: 93993-77-2
• Molecular Formula: C₁₈H₁₈O₆
• Molecular Weight: 330.3319
• Mol File: 93993-77-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 583°C at 760 mmHg
• Flash Point: 213.3°C
• Density: 1.276g/cm³
• Vapor Pressure: 3.43E-14mmHg at 25°C
• Refractive Index: 1.62
• CAS DataBase Reference: (2E)-1-(3,6-dihydroxy-2,4-dimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-1-(3,6-dihydroxy-2,4-dimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one(93993-77-2)
• EPA Substance Registry System: (2E)-1-(3,6-dihydroxy-2,4-dimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one(93993-77-2)

Safety Data

• Hazardous Substances Data: 93993-77-2(Hazardous Substances Data)

Usage

Description

(2E)-1-(3,6-dihydroxy-2,4-dimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one, commonly known as dihydromorin, is a naturally occurring chalcone derivative found in the roots of plants in the Morus genus. (2E)-1-(3,6-dihydroxy-2,4-dimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one possesses potential antioxidant and anti-inflammatory properties, making it a subject of interest for its potential health benefits and medicinal applications.
Used in Pharmaceutical Industry:
Dihydromorin is used as a potential cancer treatment agent for its inhibitory effects on the growth of cancer cells. It has demonstrated the ability to target various types of cancer, offering a promising avenue for therapeutic intervention.
Used in Diabetes Treatment:
In the medical field, dihydromorin is used as a potential treatment for diabetes due to its capacity to help regulate glucose metabolism, which can contribute to better disease management and improved patient outcomes.
Overall, (2E)-1-(3,6-dihydroxy-2,4-dimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one, or dihydromorin, is a chemical compound with significant potential in both the pharmaceutical and medical industries, particularly for cancer treatment and diabetes management. Its antioxidant and anti-inflammatory properties further contribute to its value in the pursuit of novel therapeutic agents.

Upstream product

• 3420-72-2 2'-hydroxy-4,4',6'-trimethoxychalcone 
• 15233-65-5 2,6-dimethoxy-1,4-hydroquinone 
• 530-55-2 2,6-dimethoxy-p-quinone 
• 7702-17-2 4-(acetyloxy)-3,5-dimethoxyphenyl acetate 
• 6962-57-8 3,6-dihydroxy-2,4-dimethoxyacetophenone 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 6938-19-8 6-hydroxy-5,7-dimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one 
• 481-53-8 tangeritin 
• 2798-22-3 5,8-dihydroxy-6,7-dimethoxy-2-(4-methoxyphenyl)-4-benzopyrone 
• 1168-42-9 5,6,7,4'-tetramethoxyflavone 
• 41929-26-4 1-(6-hydroxy-2,3,4-trimethoxyphenyl)-3-(4-methoxyphenyl)propenone 

Relevant articles and documents

A practical synthesis of the flavone, scutellarein

A practical and economical five-step synthesis of the flavone scutellarein has been achieved in 60% overall yield using the available and cheap 2,6-dimethoxy-1,4-benzoquinone as starting material. The reaction sequence involved reduction to the corresponding quinol, Friedel-Crafts acetylation, Claisen-Schmidt condensation with p-methoxybenzaldehyde, cyclisation and demethylation. The procedure is operationally simple and amenable to scale-up synthesis.

4',5,6,7-OXYGENATED FLAVONES AND FLAVANONES.

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