937184-70-8

Basic information

• Product Name: Dudley Reagent II, PMBO-L, PMBO-lepidine
• Synonyms: 2-(4-Methoxybenzyloxy)-4-methylquinoline;Dudley Reagent II, PMBO-L, PMBO-lepidine;PMBO-L;PMBO-lepidine
• CAS NO: 937184-70-8
• Molecular Formula: C₁₈H₁₇NO₂
• Molecular Weight: 279.33
• Mol File: 937184-70-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 73-78 °C
• Boiling Point: 435.1±35.0 °C(Predicted)
• Appearance: /
• Density: 1.155±0.06 g/cm3(Predicted)
• PKA: 3.75±0.50(Predicted)
• CAS DataBase Reference: Dudley Reagent II, PMBO-L, PMBO-lepidine(CAS DataBase Reference)
• NIST Chemistry Reference: Dudley Reagent II, PMBO-L, PMBO-lepidine(937184-70-8)
• EPA Substance Registry System: Dudley Reagent II, PMBO-L, PMBO-lepidine(937184-70-8)

Safety Data

• Hazard Codes: Xn
• Statements: 22-37/38-41
• Safety Statements: 26-39
• WGK Germany: 3
• Hazardous Substances Data: 937184-70-8(Hazardous Substances Data)

Usage

Description

Dudley Reagent II, PMBO-L, and PMBO-lepidine are chemical reagents used in organic synthesis, particularly for the protection of alcohols in various chemical reactions.

Uses

Used in Organic Synthesis:
Dudley Reagent II, PMBO-L, and PMBO-lepidine are used as protecting agents for alcohols during chemical reactions. They provide protection under relatively neutral and acidic reaction conditions, allowing for selective reactions to occur at other functional groups without affecting the alcohol moiety. This is particularly useful in the synthesis of complex organic molecules, where the selective protection and deprotection of functional groups are crucial for achieving the desired product.

Upstream product

• 634-47-9 2-chloro-4-methylquinoline 
• 105-13-5 4-Methoxybenzyl alcohol 

Downstream Products

• 2584-47-6 1,4-dimethylquinolin-2(1H)-one 
• 5405-95-8 4,4'-dimethoxydibenzyl ether 
• 548464-35-3 4-methoxybenzyl (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl ether 
• 152944-20-2 1-methoxy-4-((1-phenylethoxy)methyl)benzene 
• 212051-35-9 (R)-methyl 3-((4-methoxybenzyl)oxy)-2-methylpropanoate 
• 33999-75-6 1-((cholesteryloxy)methyl)-4-methoxybenzene 
• 104330-36-1 p-methoxybenzyl 3-phenylpropyl ether 
• 404580-71-8 (E)-1-methoxy-4-{[(3-phenylallyl)oxy]methyl}benzene 
• 512781-93-0 (4aR,7R,8R,8aS)-8-(4-Methoxy-benzyloxy)-2,2,7-trimethyl-tetrahydro-pyrano[3,2-d][1,3]dioxin-6-one 
• 115693-78-2 1,2:5,6-di-O-isopropylidene-3-O-(4-methoxybenzyl)-α-D-glucofuranose 
• 1020186-11-1 2-{[(4-methoxybenzyl)oxy]methyl}cyclohex-2-en-1-one 
• 1020186-15-5 1-(((1-ethynylcyclohexyl)oxy)methyl)-4-methoxybenzene 
• 1020186-21-3 C₂₈H₄₂O₂ 
• 1020186-18-8 C₁₅H₂₂O₂ 

Relevant articles and documents

Reagent for synthesis of para-methoxbenzyl (PMB) ethers and associated methods

A newly synthesized compound designated lepidine ether 2-(4-Methoxybenzyloxy)-4-methylquinoline reacts with methyl triflate in the presence of alcohols to generate a neutral organic salt that transfers the para-methoxybenzyl (PMB) protecting group onto al