937-13-3

Basic information

• Product Name: Oxonic Acid
• Synonyms: 4,6-dioxo-1H-1,3,5-triazine-2-carboxylic acid;2,4-Dioxo-1,2,3,4-tetrahydro-1,3,5-triazine-6-carboxylic acid;5-Azaorotic acid;4,6-Dioxo-1,4,5,6-tetrahydro-1,3,5-triazine-2-carboxylic acid;2,4-dihydroxy-1,3,5-triazine-6-carboxylic acid;Oxonic Acid;1,4,5,6-Tetrahydro-4,6-dioxo-1,3,5-triazine-2-carboxylic acid;3,4,5,6-Tetrahydro-4,6-dioxo-s-triazine-2-carboxylic acid
• CAS NO: 937-13-3
• Molecular Formula: C₄H₃N₃O₄
• Molecular Weight: 157.085
• Mol File: 937-13-3.mol
• Article Data: 1

Chemical Properties

• Melting Point: 261-261℃ (DEC.)
• Boiling Point: 771.4 °C at 760 mmHg
• Flash Point: 420.4 °C
• Appearance: /
• Density: 2.19
• PKA: -3.14±0.20(Predicted)
• CAS DataBase Reference: Oxonic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: Oxonic Acid(937-13-3)
• EPA Substance Registry System: Oxonic Acid(937-13-3)

Safety Data

• Hazardous Substances Data: 937-13-3(Hazardous Substances Data)

Usage

Description

Oxonic Acid, also known as 2-oxo-1,2,3,4-tetrahydropyrazine-6-carboxylic acid, is a chemical compound with the molecular formula C4H5NO3. It belongs to the pyrazine carboxylic acids and serves as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Oxonic Acid is used as a chiral building block in the production of various drugs, including anti-viral and anti-cancer medications. It is also utilized in the synthesis of herbicides and fungicides. Additionally, oxonic acid plays a crucial role in the development of new materials and in organic chemistry research.

Uses

Used in Pharmaceutical Industry:
Oxonic Acid is used as a chiral building block for the production of various drugs, specifically anti-viral and anti-cancer medications. Its unique structure allows for the creation of enantiomerically pure compounds, which are essential for the development of effective and safe pharmaceuticals.
Used in Agrochemical Industry:
Oxonic Acid is used as a key intermediate in the synthesis of herbicides and fungicides. Its incorporation into these products helps to improve their efficacy and selectivity, leading to better crop protection and yield.
Used in Material Development:
Oxonic Acid plays a crucial role in the development of new materials. Its unique properties and reactivity make it a valuable component in the creation of advanced materials with specific characteristics and applications.
Used in Organic Chemistry Research:
Oxonic Acid is utilized in organic chemistry research to explore new reactions, mechanisms, and synthetic pathways. Its versatility and reactivity contribute to the advancement of organic chemistry and the discovery of novel compounds and processes.

Upstream product

• 99-16-1 allantoic acid 

Downstream Products

• 108-80-5 cyanuric acid 

Relevant articles and documents

THE MECHANISM FOR THE CONVERSION OF URIC ACID INTO UROXANATE AND ALLANTOIN A NEW BASE-INDUCED 1,2-CARBOXYLATE SHIFT

Alkaline permanganate oxidation of uric acid (1), particularly the late stages of the transformation into uroxanate (7) and allantoin (3), was studied by means of isotope-position labelling.A clear-cut degradation procedure developed for distinguishing among carbonyl and α-aminal carbon atoms in these products demonstrated conclusively that the carboxylic carbon of 7 and the 4-carbonyl carbon of 3 have their origin in C(5) of uric acid (1).None of the mechanisms that have been proposed for this reaction would have predicted this result.Isotope-labelling evidence, in combination with other data, revealed the sequence of events and identities of species involved in oxidative transformation of 1; the carbon-skeleton rearrangement of the first transient intermediate 4 must occur by a 1,2-carboxylate shift to give allanatoin-5-carboxylate (6) which either decarboxylates to allantoin (3) or else undergoes hydrolytic ring opening to uroxanate (7).