93499-91-3

Basic information

• Product Name: Ethanol, 2-(trimethylsilyl)-, phenylcarbamate
• CAS NO: 93499-91-3
• Molecular Formula: C12H19NO2Si
• Molecular Weight: 237.374
• Mol File: 93499-91-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Ethanol, 2-(trimethylsilyl)-, phenylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanol, 2-(trimethylsilyl)-, phenylcarbamate(93499-91-3)
• EPA Substance Registry System: Ethanol, 2-(trimethylsilyl)-, phenylcarbamate(93499-91-3)

Safety Data

• Hazardous Substances Data: 93499-91-3(Hazardous Substances Data)

Upstream product

• 108-86-1 bromobenzene 
• 3124-37-6 carbamic acid 2-trimethylsilylethyl ester 
• 1001067-09-9 2-(trimethylsilyl)ethyl 3-nitro-1H-1,2,4-triazole-1-carboxylate 
• 62-53-3 aniline 
• 2916-68-9 2-(Trimethylsilyl)ethanol 
• 65-85-0 benzoic acid 

Downstream Products

• 2645-36-5 1-(N-phenylcarbamoyl)piperidine 
• 62-53-3 aniline 

Relevant articles and documents

Carbamic acid 2-trimethylsilylethyl ester as a new ammonia equivalent for palladium-catalyzed amination of aryl halides

Carbamic acid 2-trimethylsilylethyl ester (Teoc-NH2) serves as an ammonia equivalent in the palladium-catalyzed amination of aryl bromides and aryl chlorides. Anilines with sensitive functional groups can be readily prepared using these amine derivatives.

A FACILE SYNTHESIS OF PRIMARY AMINES FROM CARBOXYLIC ACIDS BY THE CURTIUS REARRANGEMENT

2-Trimethylsilylethanol was used to trap isocyanates produced by the Curtius rearrangement of acyl azides and the resulting trimethylsilylethyl carbamates were readily cleaved with tetra-n-butylammonium fluoride to liberate the primary amines.