92934-63-9

Basic information

• Product Name: (+)-Tropicamide
• Synonyms: Benzeneacetamide, N-ethyl-a-(hydroxymethyl)-N-(4-pyridinylmethyl)-, (aR)- (9CI);Benzeneacetamide, N-ethyl-a-(hydroxymethyl)-N-(4-pyridinylmethyl)-, (R)-
• CAS NO: 92934-63-9
• Molecular Weight: 0
• Mol File: 92934-63-9.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (+)-Tropicamide(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-Tropicamide(92934-63-9)
• EPA Substance Registry System: (+)-Tropicamide(92934-63-9)

Safety Data

• Hazardous Substances Data: 92934-63-9(Hazardous Substances Data)

Usage

Description

(+)-Tropicamide is a medication that functions as a muscarinic acetylcholine receptor antagonist, which is used in eye drops to dilate the pupil and temporarily paralyze the ciliary muscle of the eye. This property aids in the examination and treatment of certain eye conditions by blocking the action of acetylcholine at these receptors in the eye, leading to pupil dilation and paralysis of the ciliary muscle. The effects of (+)-Tropicamide typically last for a few hours, making it a useful tool for eye examinations and procedures.

Uses

Used in Ophthalmology:
(+)-Tropicamide is used as a diagnostic and therapeutic agent for eye conditions, facilitating the examination and treatment process. It is particularly useful for:
1. Pupil Dilation: As a muscarinic acetylcholine receptor antagonist, (+)-Tropicamide is used to dilate the pupil, which is essential for comprehensive eye examinations and the diagnosis of various eye conditions.
2. Temporary Paralysis of the Ciliary Muscle: It is used to temporarily paralyze the ciliary muscle, which helps in the assessment of the eye's refractive state and the fitting of corrective lenses.
3. Examination and Treatment of Certain Eye Conditions: The dilation of the pupil and paralysis of the ciliary muscle provided by (+)-Tropicamide enable ophthalmologists to better examine the eye's interior, diagnose conditions, and administer appropriate treatments.
While (+)-Tropicamide is a valuable tool in ophthalmology, it can cause side effects such as blurred vision, increased sensitivity to light, and temporary stinging or discomfort in the eyes. Despite these potential side effects, its benefits in facilitating eye examinations and treatments make it an important medication in the field of ophthalmology.

Upstream product

• 14510-37-3 3-acetoxy-2-phenyl-propionyl chloride 
• 33403-97-3 4-(ETHYLAMINOMETHYL)PYRIDINE 
• 1508-75-4 tropicamide 
• 177567-33-8 Acetic acid (R)-2-(ethyl-pyridin-4-ylmethyl-carbamoyl)-2-phenyl-ethyl ester 
• 177567-34-9 Acetic acid (S)-2-(ethyl-pyridin-4-ylmethyl-carbamoyl)-2-phenyl-ethyl ester 
• 67-56-1 methanol 
• 33262-90-7 N-ethyl-2-phenyl-N-pyridin-4-ylmethyl-acetamide 
• 103-80-0 phenylacetyl chloride 
• 529-64-6 Tropic acid 
• 37504-67-9 α-[(acetyloxy)methyl]benzeneacetic acid 
• 872-85-5 pyridine-4-carbaldehyde 
• 54433-74-8 Ethyl-[1-pyridin-4-yl-meth-(E)-ylidene]-amine 
• 17097-90-4 2-phenylmalonic acid monoethyl ester 
• 83-13-6 diethyl 2-phenylmalonate 

Relevant articles and documents

Cobalt-catalyzed direct α-hydroxymethylation of amides with methanol as a C1 source

Herein, we report a cobalt-catalyzed α-hydroxymethylation of amides with methanol under mild conditions. Using CoCl2·6H2O as an inexpensive and efficient catalyst, some important bioactive β-hydroxyamides were obtained in moderate to excellent yields. The

Process for preparing N- ethylpyridine methylamine hydrochloride crystal, and application thereof in preparation of itemamide (by machine translation)

An application N - of,ethylpyridine methylamine hydrochloride crystal, prepared by dissolving N -ethylpyridine methylamine N - in an organic solvent, at room temperature or heating X - in an organic solvent is stirred until the material is completely dissolved, is stirred until the material is completely dissolved or stirred at about 9.73 °, 14.61 °, 17.98 °, 18.49 °, 20.36 °, 24.63 °, 27.21 ° with a diffraction peak, and is stirred. N - through a,ray powder diffractogram, for drying to obtain the supported product amide key starting material, ethyl-pyridine methylamine hydrochloride; is prepared by filtering, and drying. The crystal has the advantages of simple operation, purification effect, crystallization and high N -purity crystal, form impurity content in the, preparation of the itemamide hydrochloride, crystal . and is, simple and convenient, operation. (by machine translation)

N- Ethylpyridine methylamine hydrochloride and crystal, preparation process and application thereof

The invention discloses N -ethyl-pyridine methylamine trifluoroacetate, and a crystal. preparation process and application N - thereof to prepare N -ethylpyridine methylamine hydrochloride crystals, by slowly adding X -ethyl-pyridine methylamine, in an organic solvent 15.12 °, 15.45 °, 17.68 °, 20.68 °, 22.62 °, 23.25 °, 24.75 °, 29.54 ° at room temperature or heating. to fully dissolve N -ethyl-pyridine methylamine . through heating for, hours to prepare the ethyl-pyridine methylamine trifluoroacetate crystals . The method is simple in operation and;% in crystal form impurity content, obtained by dry-adding trifluoroacetic acid; crystals, at about, at room temperature or, in a heating mode of heating the crystals at a temperature ranging from, N - degrees, to a. material completely-dissolving solution.