928712-61-2

Basic information

• Product Name: α-Hydroxy-4-methoxy-α-phenylbenzeneacetic acid methyl ester
• Synonyms: α-Hydroxy-4-methoxy-α-phenylbenzeneacetic acid methyl ester
• CAS NO: 928712-61-2
• Molecular Weight: 272.301
• Mol File: 928712-61-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: α-Hydroxy-4-methoxy-α-phenylbenzeneacetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: α-Hydroxy-4-methoxy-α-phenylbenzeneacetic acid methyl ester(928712-61-2)
• EPA Substance Registry System: α-Hydroxy-4-methoxy-α-phenylbenzeneacetic acid methyl ester(928712-61-2)

Safety Data

• Hazardous Substances Data: 928712-61-2(Hazardous Substances Data)

Upstream product

• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 13139-86-1 4-methoxyphenyl magnesium bromide 

Downstream Products

• 1373335-21-7 6-hydroxy-3-(4-methoxyphenyl)-3-phenylbenzofuran-2-(3H)-one 
• 5359-50-2 methyl 2-(4-methoxyphenyl)-2-phenylacetate 
• 4237-50-7 (R)-2-hydroxy-2-(4-methoxyphenyl)-2-phenylacetic acid 
• 95431-41-7 Methyl-4.4'-dimethoxy-triphenylacetat 

Relevant articles and documents

Synthesis of Chiral Triarylmethanes Bearing All-Carbon Quaternary Stereocenters: Catalytic Asymmetric Oxidative Cross-Coupling of 2,2-Diarylacetonitriles and (Hetero)arenes

A direct and enantioselective oxidative cross-coupling of racemic 2,2-diarylacetonitriles with electron-rich (hetero)arenes has been described, which allows for efficient construction of triarylmethanes bearing all-carbon quaternary stereocenters with excellent chemo- and enantioselectivity. The reaction has an excellent functional group tolerance, and exhibits a broad scope with respect to both 2,2-diarylacetonitrile and (hetero)arene components. The rich chemistry of the cyano group allows for facile synthesis of other valuable chiral triarylmethanes bearing all-carbon quaternary centers that are otherwise difficult to access.