928053-26-3

Basic information

• Product Name: (4S,7R)-2-(2,4-difluoro-phenyl)-7,8,8-trimethyl-1,2,4,5,6,7-hexahydro-4,7-methano-indazol-3-one
• Synonyms: (4S,7R)-2-(2,4-difluoro-phenyl)-7,8,8-trimethyl-1,2,4,5,6,7-hexahydro-4,7-methano-indazol-3-one
• CAS NO: 928053-26-3
• Molecular Weight: 304.34
• Mol File: 928053-26-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4S,7R)-2-(2,4-difluoro-phenyl)-7,8,8-trimethyl-1,2,4,5,6,7-hexahydro-4,7-methano-indazol-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,7R)-2-(2,4-difluoro-phenyl)-7,8,8-trimethyl-1,2,4,5,6,7-hexahydro-4,7-methano-indazol-3-one(928053-26-3)
• EPA Substance Registry System: (4S,7R)-2-(2,4-difluoro-phenyl)-7,8,8-trimethyl-1,2,4,5,6,7-hexahydro-4,7-methano-indazol-3-one(928053-26-3)

Safety Data

• Hazardous Substances Data: 928053-26-3(Hazardous Substances Data)

Upstream product

• 928053-37-6 N-(2,4-difluoro-phenyl)-N'-ethylidene-hydrazine 
• 72690-88-1 D-(+)-3-camphoryl chloride 
• 40594-30-7 2,4-difluorophenylhydrazine 
• 22469-70-1 (1R,4R)-4,7,7-trimethyl-3-oxo-bicyclo[2.2.1]heptane-2-carboxylic acid ethyl ester 

Downstream Products

• 928052-66-8 (4S,7R)-2-(2,4-difluoro-phenyl)-7,8,8-trimethyl-1-(3-oxo-3-phenyl-propyl)-1,2,4,5,6,7-hexahydro-4,7-methano-indazol-3-one 
• 928052-30-6 (4S,7R)-1-allyl-2-(2,4-difluoro-phenyl)-7,8,8-trimethyl-1,2,4,5,6,7-hexahydro-4,7-methano-indazol-3-one 

Relevant articles and documents

Pyrazolones as inhibitors of 11B-hydroxysteroid dehydrogenase

Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, type II diabetes mellitus and metabolic syndrome.