92409-23-9

Basic information

• Product Name: 3-Hydroxy-2-(2-methoxyphenoxy)-1-(4-methoxyphenyl)propan-1-one
• Synonyms: 3-Hydroxy-2-(2-methoxyphenoxy)-1-(4-methoxyphenyl)propan-1-one
• CAS NO: 92409-23-9
• Molecular Formula: C₁₇H₁₈O₅
• Molecular Weight: 302.32182
• Mol File: 92409-23-9.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 494.7±45.0 °C(Predicted)
• Appearance: /
• Density: 1.200±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 13.67±0.10(Predicted)
• CAS DataBase Reference: 3-Hydroxy-2-(2-methoxyphenoxy)-1-(4-methoxyphenyl)propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Hydroxy-2-(2-methoxyphenoxy)-1-(4-methoxyphenyl)propan-1-one(92409-23-9)
• EPA Substance Registry System: 3-Hydroxy-2-(2-methoxyphenoxy)-1-(4-methoxyphenyl)propan-1-one(92409-23-9)

Safety Data

• Hazardous Substances Data: 92409-23-9(Hazardous Substances Data)

Usage

Description

3-Hydroxy-2-(2-methoxyphenoxy)-1-(4-methoxyphenyl)propan-1-one is a chemical compound with a propanone backbone that is attached to two aromatic rings, one featuring a methoxy group and the other a hydroxy group. This unique structure endows it with potential applications in various fields, particularly in organic chemistry and medicinal chemistry.

Uses

Used in Pharmaceutical Synthesis:
3-Hydroxy-2-(2-methoxyphenoxy)-1-(4-methoxyphenyl)propan-1-one is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs. Its specific structural features allow it to be a valuable component in creating complex organic compounds that can address various medical needs.
Used in Organic Chemistry Research:
In the field of organic chemistry, 3-Hydroxy-2-(2-methoxyphenoxy)-1-(4-methoxyphenyl)propan-1-one is used as a reagent to explore new reactions and mechanisms. Its distinct structure provides a platform for understanding how different functional groups can interact and influence chemical behavior.
Used in Medicinal Chemistry and Drug Development:
3-Hydroxy-2-(2-methoxyphenoxy)-1-(4-methoxyphenyl)propan-1-one is utilized as a building block in medicinal chemistry for the design and synthesis of potential drug candidates. Its incorporation into molecular structures can lead to the discovery of new therapeutic agents with improved efficacy and selectivity.
It is crucial to handle 3-Hydroxy-2-(2-methoxyphenoxy)-1-(4-methoxyphenyl)propan-1-one with care due to its potential health and environmental hazards if mismanaged. Proper safety measures should be taken to mitigate any risks associated with its use in research and development.

Upstream product

• 13078-21-2 ethyl 2-(2-methoxyphenoxy)acetate 
• 5000-65-7 2-bromo-3'-methoxyacetophenone 
• 586-37-8 1-(3-Methoxyphenyl)ethanone 
• 90-05-1 2-methoxy-phenol 
• 2632-13-5 2-Bromo-4'-methoxyacetophenone 
• 92409-15-9 2-(2-methoxyphenoxy)-1-(4-methoxyphenyl)-1-hydroxy-3-propanol 
• 535967-82-9 1-(4-(benzyloxy)-3,5-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propan-1-one 
• 10548-77-3 1-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propan-1-one 
• 19513-80-5 2-(2-methoxyphenoxy)-1-(4-methoxyphenyl)ethan-1-one 
• 151541-15-0 ethyl 3-(4-(benzyloxy)-3,5-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propanoate 
• 94687-10-2 ethyl-3-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propanoate 
• 50-00-0 formaldehyd 
• 70110-66-6 3-(3,4-dimethoxyphenyl)-3-ethoxy-2-(2-methoxyphenoxy)propan-1-ol 
• 535967-76-1 1-(4-(benzyloxy)-3,5-dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol 

Downstream Products

• 92409-15-9 2-(2-methoxyphenoxy)-1-(4-methoxyphenyl)-1-hydroxy-3-propanol 
• 90-05-1 2-methoxy-phenol 
• 6437-46-3 1-(2-methoxyphenoxy)propan-2-one 
• 61428-20-4 3-(4-methoxyphenyl)isoxazole 
• 874-90-8 4-methoxybenzonitrile 
• 27069-17-6 3-p-methoxyphenylpyrazole 
• 100-09-4 4-methoxybenzoic acid 
• 150-76-5 4-methoxy-phenol 
• 106-51-4 p-benzoquinone 
• 150-19-6 O-methylresorcine 
• 56122-35-1 1-(4-(benzyloxy)phenyl)-2-(2-methoxyphenoxy)ethan-1-one 
• 56122-36-2 3-hydroxy-1-(4-(benzyloxy)phenyl)-2-(2-methoxyphenoxy)propan-1-one 
• 99634-01-2 3-hydroxy-2-(2-methoxyphenoxy)-1-phenyl-1-propanone 
• 14385-48-9 2-(2-methoxyphenoxy)-acetophenone 

Relevant articles and documents

Photophysics of Perylene Diimide Dianions and Their Application in Photoredox Catalysis

The two-electron reduced forms of perylene diimides (PDIs) are luminescent closed-shell species whose photochemical properties seem underexplored. Our proof-of-concept study demonstrates that straightforward (single) excitation of PDI dianions with green

Cleavage∕cross-coupling strategy for converting β-O-4 linkage lignin model compounds into high valued benzyl amines via dual C–O bond cleavage

Lignin is the most recalcitrant of the three components of lignocellulosic biomass. The strength and stability of the linkages have long been a great challenge for the degradation and valorization of lignin biomass to obtain bio-fuels and commercial chemicals. Up to now, the selective cleavage of C–O linkages of lignin to afford chemicals contains only C, H and O atoms. Our group has developed a cleavage/cross-coupling strategy for converting 4-O-5 linkage lignin model compounds into high value-added compounds. Herein, we present a palladium-catalyzed cleavage/cross-coupling of the β-O-4 lignin model compounds with amines via dual C–O bond cleavage for the preparation of benzyl amine compounds and phenols.

A multicentre synergistic polyoxometalate-based metal-organic framework for one-step selective oxidative cleavage of β-: O -4 lignin model compounds

A novel mixed-valence polyoxovanadate-based copper-organic framework, [CuI(bbi)]2{[CuI(bbi)]2VIV2VV8O26}·2H2O (NENU-MV-5, bbi = 1,1′-(1,4-butanediyl)bis(imidazole)), was facilely synthesized from routine reagents under mild hydrothermal conditions. Using NENU-MV-5 as a heterogeneous catalyst without any co-catalyst, one-step oxidative cleavage of β-O-4 lignin into phenols and aromatic acids with high catalytic activity and selectivity was realized under an oxygen atmosphere. No obvious decrease in activity was observed after five cycles, which indicates the excellent stability and sustainability of NENU-MV-5. The perfect catalytic performance of NENU-MV-5 can be attributed to the multi-site synergistic effect of the mixed-valence VV-O-VIV sites on polyoxovanadate for the oxidation of β-O-4 alcohol to β-O-4 ketone and the Cu(i) sites on the framework for the rapid cleavage of the Cα-Cβ bond of β-O-4 ketone. This system represented the first co-catalyst-free example for the one-step selective degradation of lignin catalyzed by a well-defined crystalline catalyst with definite composition and structure in a single solvent.