923565-05-3

Basic information

• Product Name: 3',4',5,7-tetra-O-benzyl-8-bromocatechin-4α,8-(3',4',5,7-tetra-O-benzylepicatechin)
• Synonyms: 3',4',5,7-tetra-O-benzyl-8-bromocatechin-4α,8-(3',4',5,7-tetra-O-benzylepicatechin)
• CAS NO: 923565-05-3
• Molecular Weight: 1378.42
• Mol File: 923565-05-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3',4',5,7-tetra-O-benzyl-8-bromocatechin-4α,8-(3',4',5,7-tetra-O-benzylepicatechin)(CAS DataBase Reference)
• NIST Chemistry Reference: 3',4',5,7-tetra-O-benzyl-8-bromocatechin-4α,8-(3',4',5,7-tetra-O-benzylepicatechin)(923565-05-3)
• EPA Substance Registry System: 3',4',5,7-tetra-O-benzyl-8-bromocatechin-4α,8-(3',4',5,7-tetra-O-benzylepicatechin)(923565-05-3)

Safety Data

• Hazardous Substances Data: 923565-05-3(Hazardous Substances Data)

Upstream product

• 923565-00-8 3’,4’,5,7-tetra-O-benzyl-4β-(2-hydroxyethyloxy)-8-bromocatechin 
• 87292-49-7 5,7,3',4'-tetra-O-benzylepicatechin 
• 100-39-0 benzyl bromide 
• 20728-73-8 5,7,3',4'-tetra-O-benzyl-(+)-catechin 
• 256236-21-2 5,7,3',4'-tetra-O-benzyl-8-bromocatechin 
• 490-46-0 (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol 
• 154-23-4 catechin 
• 223387-51-7 (2R,3S,4S)-5,7,3',4'-tetrabenzyloxy-4-(2-hydroxyethyloxy)flavan-3-ol 

Downstream Products

• 29106-51-2 procyanidin B₄ 

Relevant articles and documents

An improved synthesis of procyanidin dimers: Regio- and stereocontrol of the interflavan bond

A direct and general synthesis of procyanidin dimers B1, B2, B3 and B4 (10a-d) is presented. The approach is based on the stoichiometric coupling of two protected monomeric units (the nucleophilic 2a-b and electrophilic 4a-b partners) and deals with the regio- and stereocontrol of the C4-C8 interflavan bond as well as the control of the degree of oligomerization. The synthesis involves a five-step pathway starting from the native catechin (1a) or epicatechin (1b) to the fully deprotected dimers 10a-d. Furthermore, the process appears to be iterative as the coupling intermediates 9a-d themselves can be readily used in further selective syntheses of trimers or higher oligomers. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.