918793-63-2

Basic information

• Product Name: Boronic acid, B-[(1E)-1,2-diphenyl-1-buten-1-yl]-
• CAS NO: 918793-63-2
• Molecular Formula: C16H17BO2
• Molecular Weight: 252.121
• Mol File: 918793-63-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Boronic acid, B-[(1E)-1,2-diphenyl-1-buten-1-yl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Boronic acid, B-[(1E)-1,2-diphenyl-1-buten-1-yl]-(918793-63-2)
• EPA Substance Registry System: Boronic acid, B-[(1E)-1,2-diphenyl-1-buten-1-yl]-(918793-63-2)

Safety Data

• Hazardous Substances Data: 918793-63-2(Hazardous Substances Data)

Upstream product

• 811-49-4 ethyllithium 
• 501-65-5 diphenyl acetylene 

Downstream Products

• 16282-16-9 1,2-diphenyl-butan-1-one 
• 10540-29-1 tamoxifen 
• 13002-65-8 (E)-tamoxifen 

Relevant articles and documents

Carbolithiation of diphenylacetylene as a stereoselective route to (Z)-tamoxifen and related tetrasubstituted olefins

(Chemical Equation Presented) Carbolithiation of diphenylacetylene can be exploited to generate (E)-1-lithio-1,2-diphenylalkyl-1-enes which can be reacted in situ with triisopropylborate to stereoselectively provide (E)-1,2-diphenyl-1-alkylene boronic acids. These tetrasubstituted vinylboronic acids served as versatile intermediates for the generation of tetrasubstituted olefins with retention of stereochemistry. The application of this method for the stereoselective synthesis of (Z)-tamoxifen and related analogues is described.