90780-55-5 Usage
Description
(+/-)7-HDOHE, also known as (±)7-Hydroxy-4Z,8E,10Z,13Z,16Z,19Z-docosahexaenoic Acid, is an auto-oxidation product of DHA (D494500), an omega-3 fatty acid found in marine fish oils and in many phospholipids. It plays a crucial role as a major structural component of excitable membranes of the retina and brain and is synthesized in the liver from α-linolenic acid.
Uses
Used in Nutritional Supplements:
(+/-)7-HDOHE is used as a nutritional supplement for its omega-3 fatty acid content, which is essential for maintaining the health and function of the retina and brain. It is particularly beneficial for individuals who may not be getting enough omega-3 fatty acids from their diet or for those who require additional support for cognitive and visual health.
Check Digit Verification of cas no
The CAS Registry Mumber 90780-55-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,7,8 and 0 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 90780-55:
(7*9)+(6*0)+(5*7)+(4*8)+(3*0)+(2*5)+(1*5)=145
145 % 10 = 5
So 90780-55-5 is a valid CAS Registry Number.
90780-55-5Relevant articles and documents
Enantioselective Synthesis of 7(S)-Hydroxydocosahexaenoic Acid, a Possible Endogenous Ligand for PPARα
Zhang, Minhao,Sayyad, Ashik A.,Dhesi, Anmol,Orellana, Arturo
, p. 13621 - 13629 (2020)
We report the first total synthesis of the polyunsaturated fatty acid 7-hydroxydocosahexaenoic acid (7-HDHA) in racemic form and the enantioselective synthesis of 7-(S)-HDHA. Both syntheses follow a convergent approach that unites the C1-C9 and C10-C22 fragments using Sonogashira coupling and Boland reduction as key steps. These syntheses enabled the unambiguous characterization of this natural product for the first time and helped establish 7(S)-HDHA as a possible endogenous ligand for peroxisome proliferator-activated receptor alpha.
