9007-81-2 Usage
Description
Freund's Complete Adjuvant (FCA) is a potent immunological adjuvant used to enhance the body's immune response to antigens. It is a mixture of inactivated Mycobacterium tuberculosis, mineral oil, and mannide monooleate, which stimulates both the humoral and cellular immune systems. FCA is commonly used in research settings to study immune responses and develop vaccines.
Uses
Used in Immunization:
Freund's Complete Adjuvant is used as an immunological adjuvant to enhance the body's immune response to antigens. It is typically mixed with an equal volume of antigens (preferably in saline) to form an emulsion, which is then injected into animals to stimulate a robust immune response.
Used in Vaccine Development:
FCA is used in the development of vaccines to improve their efficacy by enhancing the immune response to the antigens present in the vaccine. It helps in the production of high levels of antibodies and the activation of immune cells, which can provide long-lasting immunity against the target pathogen.
Used in Research:
Freund's Complete Adjuvant is used in various research applications to study immune responses, including the investigation of autoimmune diseases, allergy, and the development of new immunotherapies. It is also used to generate animal models for the study of immune system function and the evaluation of novel therapeutic agents.
Used in Diagnostics:
FCA can be used in the development of diagnostic tests for the detection of antibodies or immune cells specific to certain antigens. By enhancing the immune response, FCA can help improve the sensitivity and specificity of diagnostic assays.
General Description:
Freund's Complete Adjuvant is typically supplied as a set of 10 x 10 ml vials, each containing a yellow, oily, bacterial suspension. It should be stored at 2-8°C and protected from light to maintain its stability and potency.
Biochem/physiol Actions
The mycobacteria in Complete Freund′s adjuvant attracts macrophages and other cells to the injection site which enhances the immune response. For this reason, Complete Freund′s Adjuvant is used for initial injections and Incomplete Freund′s Adjuvant for subsequent boosts.
Check Digit Verification of cas no
The CAS Registry Mumber 9007-81-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,0 and 7 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 9007-81:
(6*9)+(5*0)+(4*0)+(3*7)+(2*8)+(1*1)=92
92 % 10 = 2
So 9007-81-2 is a valid CAS Registry Number.
