9005-67-8

Basic information

• Product Name: Tween 60
• Synonyms: FEMA 2916;T-61;PEG-3 SORBITAN STEARATE;PEG-6 SORBITAN STEARATE;PEG-40 SORBITAN STEARATE;PEG-60 SORBITAN STEARATE;POLYOXYETHYLENESORBITAN MONOSTEARATE*(TW EEN 61);POLYOXYETHYLENESORBITAN MONOSTEARATE*TWE EN 60
• CAS NO: 9005-67-8
• Molecular Formula: C64H126O26
• Molecular Weight: 0
• EINECS: -0
• Product Categories: Ester Ether Type (Surfactants);Functional Materials;Nonionic Surfactants;Surfactants;Biochemistry;Nonionic Surfactants (for Biochemistry);Surfactants (for Biochemistry);Cosmetic Ingredients & Chemicals;Detergents;Detergents A to ZDetergents;Non-Ionic
• Mol File: 9005-67-8.mol
• Article Data: 0

Chemical Properties

• Melting Point: 45-50 °C
• Boiling Point: 802.68°C (rough estimate)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.044 g/mL at 25 °C(lit.)
• Vapor Pressure: 4.64E-16mmHg at 25°C
• Refractive Index: n20/D 1.474
• Storage Temp.: Store at RT.
• Solubility: 100 g/L
• PKA: 0[at 20 ℃]
• Water Solubility: 100 g/L
• Merck: 14,7582
• CAS DataBase Reference: Tween 60(CAS DataBase Reference)
• NIST Chemistry Reference: Tween 60(9005-67-8)
• EPA Substance Registry System: Tween 60(9005-67-8)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 1
• RTECS: WG2934000
• TSCA: Yes
• Hazardous Substances Data: 9005-67-8(Hazardous Substances Data)

Usage

Description

Tween 60, also known as polysorbate 60, is a nonionic, water-dispersible surface-active agent that is very hydrophilic. It is a polymer composed of PEG-ylated sorbitan, where the total number of poly(ethylene glycol) units is 20 and a single terminal is capped by a stearate group. It is manufactured by reacting stearic acid with sorbitol and then reacting the product with ethylene oxide. It has a faint, characteristic odor and a warm, somewhat bitter taste.

Uses

Used in Plastic & Polymers Industry:
Tween 60 is used as an emulsifier for plastic and polymer applications, such as Lonzest(R) SMS-20.
Used in Personal Care Industry:
Tween 60 is used as an emulsifier in personal care products, such as Glycosperse(R) S-20 KFG. Suggested applications include cakes, shortenings, milk substitute, and chocolate-flavored syrup.
Used in Food Industry:
Tween 60 is used as an emulsifier in various food products, such as whipped vegetable toppings for overrun and lightness, cakes for increased volume and fine grain, icings and confectionery for lightness and syneresis control, and salad dressing for emulsion stability. It is frequently used with sorbitan monostearate or mono and diglycerides, with a typical usage range of 0.10-0.40%.
Used in Pharmaceutical Industry:
Tween 60 is used as an emulsifier in the formulation of azalide antibiotics.
Used in Niosome Formulations:
Tween 60 is used in the formulation of niosomes, which are vesicular systems made from non-ionic surfactants, for various pharmaceutical and cosmetic applications.

Flammability and Explosibility

Nonflammable

Safety Profile

Moderately toxic by intravenous route. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits acrid smoke and irritating fumes.

InChI:InChI=1/C22H42O8/c1-2-3-4-5-6-7-8-9-10-11-20(26)29-16-18(25)21-22(28-15-13-24)19(17-30-21)27-14-12-23/h18-19,21-25H,2-17H2,1H3/t18-,19+,21-,22-/m1/s1