886761-96-2 Usage
General Description
2-Bromo-5-fluorophenylacetonitrile is a chemical compound with the molecular formula C8H5BrFN. It is an organic nitrile derivative, containing a nitrile functional group and a bromine atom bonded to a phenyl ring with a fluorine substituent. 2-BROMO-5-FLUOROPHENYLACETONITRILE is commonly used in the pharmaceutical and chemical industries as an intermediate for the synthesis of various pharmaceuticals, agrochemicals, and fine chemicals. It is also used as a building block in the preparation of diverse organic compounds and complex molecules. The compound's specific chemical properties and reactivity make it a valuable tool for producing a wide range of products in the chemical and pharmaceutical sectors. Due to its versatility and wide applicability, 2-bromo-5-fluorophenylacetonitrile is a significant compound in modern industrial chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 886761-96-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,6,7,6 and 1 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 886761-96:
(8*8)+(7*8)+(6*6)+(5*7)+(4*6)+(3*1)+(2*9)+(1*6)=242
242 % 10 = 2
So 886761-96-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H5BrFN/c9-8-2-1-7(10)5-6(8)3-4-11/h1-2,5H,3H2
886761-96-2Relevant articles and documents
Highly diastereoselective synthesis of tetralin-fused spirooxindoles via lewis acid-catalyzed C(sp3)H bond functionalization
Machida, Mizuki,Mori, Keiji
supporting information, p. 868 - 871 (2018/07/03)
A highly diastereoselective synthesis of tetralin-fused spirooxindole derivatives was described. Treatment of benzylidene oxindoles with a catalytic amount of Sc(OTf)3 in refluxing hexane afforded the target compounds in good chemical yields with excellent diastereoselectivities (up to >20:1). Detailed investigation of the reaction mechanism revealed that both interconversion of the two diastereomers and their solubility difference in reaction medium were the key to achieving excellent diastereoselectivities.
Synthesis of benzylisoquinoline derivatives possessing electron-withdrawing substituents on the benzene ring of the isoquinoline skeleton
Severin, René,Mujahidin, Didin,Reimer, Jessica,Doye, Sven
, p. 683 - 700 (2008/09/18)
3,4-Dihydrobenzylisoquinolines and 1,2,3,4-tetrahydrobenzyl-isoquinolines possessing electron withdrawing substituents on the benzene ring of the isoquinoline framework are easily accessible by a synthetic approach that takes advantage of a Sonogashira coupling to build up the C1-C8a bond of the isoquinoline skeleton and a Ti-catalyzed intramolecular hydroamination of an alkyne to close the heterocyclic ring.
