88188-06-1

Basic information

• Product Name: Trimethylsilyl trifluoromethanesulphonate
• CAS NO: 88188-06-1
• Molecular Formula: C₄H₉F₃O₃SSi
• Molecular Weight: 206.261
• Mol File: 88188-06-1.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 140°Cat760mmHg
• Flash Point: 38.5°C
• Density: 1.276g/cm³
• CAS DataBase Reference: Trimethylsilyl trifluoromethanesulphonate(CAS DataBase Reference)
• NIST Chemistry Reference: Trimethylsilyl trifluoromethanesulphonate(88188-06-1)
• EPA Substance Registry System: Trimethylsilyl trifluoromethanesulphonate(88188-06-1)

Safety Data

• Hazardous Substances Data: 88188-06-1(Hazardous Substances Data)

Usage

General Description

Trimethylsilyl trifluoromethanesulphonate, also known as TMSOTf, is a versatile and powerful chemical reagent frequently used in organic synthesis. Trimethylsilyl trifluoromethanesulphonate features a trimethylsilyl group attached to a trifluoromethanesulfonyl moiety, giving it strong acidity and high reactivity. TMSOTf is commonly employed as a Lewis acid catalyst in various reactions, such as transesterification, cyclization, and protection of sensitive functional groups. Additionally, it is crucial in the synthesis of complex molecules and natural products due to its ability to activate nucleophiles and promote efficient bond formation. Overall, TMSOTf plays a significant role in modern organic chemistry as a key reagent for carrying out a wide range of chemical transformations.

Downstream Products

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• 1189362-64-8 C₄₇H₆₇F₃O₁₂SSi 
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