88059-40-9Relevant articles and documents
The Chemistry of 2H-3,1-Benzoxazine-2,4(1H)-dione (Isatoic Anhydride). 11. Reaction of N-Methylisatoic Anhydride with 1-Cyanoacetylpiperidine
Coppola, Gary M.,Fu, Emil W.,Shapiro, Michael J.,Hartdmann, Goetz E.
, p. 1427 - 1429 (2007/10/02)
The reaction of N-methylisatoic anhydride with 1-cyanoacetylpiperidine in the presence of sodium hydride produces a tautomeric mixture of 4a and 4b, with 4b predominating.When heated in xylene, 4 is converted to the piperidine adduct 5 whereas heating in dimethyl sulfoxide furnishes 3.Spectral data for 4 and 5 are also discussed.