874908-14-2 Usage
Chemical Properties
Pale Yellow Solid
Uses
A metabolite of Repaglinide (R144500).
Check Digit Verification of cas no
The CAS Registry Mumber 874908-14-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,4,9,0 and 8 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 874908-14:
(8*8)+(7*7)+(6*4)+(5*9)+(4*0)+(3*8)+(2*1)+(1*4)=212
212 % 10 = 2
So 874908-14-2 is a valid CAS Registry Number.
InChI:InChI=1/C27H36N2O5/c1-4-34-25-15-19(11-12-22(25)27(32)33)16-26(31)28-23(14-18(2)3)21-9-5-6-10-24(21)29-13-7-8-20(30)17-29/h5-6,9-12,15,18,20,23,30H,4,7-8,13-14,16-17H2,1-3H3,(H,28,31)(H,32,33)
874908-14-2Relevant articles and documents
Influence of CYP2C8 polymorphisms on the hydroxylation metabolism of paclitaxel, repaglinide and ibuprofen enantiomers in vitro
Yu, Lushan,Shi, Da,Ma, Liping,Zhou, Quan,Zeng, Su
, p. 278 - 287 (2013)
CYP2C8 plays an important role in the metabolism of various drugs, such as paclitaxel, repaglinide and ibuprofen. Polymorphisms in the CYP2C8 gene were shown to influence interindividual differences in the pharmacokinetics of paclitaxel, repaglinide and i