874-42-0 Usage
Description
2,4-Dichlorobenzaldehyde is an organic compound characterized by the presence of two chlorine atoms at the 2nd and 4th positions on a benzene ring, with an aldehyde functional group attached to the carbonyl group. It is a versatile intermediate in organic synthesis and possesses unique chemical properties due to the presence of chlorine atoms.
Uses
Used in Pharmaceutical Industry:
2,4-Dichlorobenzaldehyde is used as a key intermediate in the synthesis of platelet aggregation inhibitors, which are important for the development of medications aimed at preventing blood clot formation and treating cardiovascular diseases.
Used in Organic Chemistry Research:
2,4-Dichlorobenzaldehyde is utilized in the preparation of novel Schiff bases containing quinazolinone rings. These compounds have potential applications in various fields, including pharmaceuticals, materials science, and as chemical sensors.
Used in Solid-Phase Synthesis:
2,4-Dichlorobenzaldehyde was employed in the solid-phase synthesis of a series of indole-based peptoids. This technique allows for the efficient and scalable production of peptoid libraries, which have potential applications in drug discovery and the development of bioactive molecules.
Synthesis Reference(s)
Tetrahedron Letters, 30, p. 3677, 1989 DOI: 10.1016/S0040-4039(01)80481-0
Air & Water Reactions
Sensitive to light. May also be sensitive to prolonged exposure to air and moisture. Insoluble in water.
Reactivity Profile
2,4-Dichlorobenzaldehyde is incompatible with iron, oxygen and oxygen-containing materials. 2,4-Dichlorobenzaldehyde is also incompatible with strong oxidizers and strong bases.
Fire Hazard
2,4-Dichlorobenzaldehyde is combustible.
Purification Methods
Crystallise the aldehyde from EtOH or ligroin. [Beilstein 7 IV 575.]
Check Digit Verification of cas no
The CAS Registry Mumber 874-42-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,7 and 4 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 874-42:
(5*8)+(4*7)+(3*4)+(2*4)+(1*2)=90
90 % 10 = 0
So 874-42-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H4Cl2O/c8-6-2-1-5(4-10)7(9)3-6/h1-4H
874-42-0Relevant articles and documents
MoO: x-pyridine organic-inorganic hybrid wires as a reusable and highly selective catalyst for the oxidation of alcohols: a comparison study between reaction-controlled phase-transfer catalysis and heterogeneous catalysis
Malakooti,Feghhi
, p. 3405 - 3413 (2017)
The different catalytic behaviors of Mo3O10(C5H6N)2·H2O wires (MoOx-pyridine) in the selective oxidation of alcohols by means of molecular oxygen (O2) and hydrogen per
New Stable Catalytic Electrodes Functionalized with TEMPO for the Waste-Free Oxidation of Alcohol
Karimi, Babak,Ghahremani, Mina,Ciriminna, Rosaria,Pagliaro, Mario
, p. 1298 - 1305 (2018)
We report the first catalytically active and stable sol-gel electrode functionalized with the TEMPO moiety for the highly selective oxidation of alcohols with an electric current only. The method shows broad applicability to different substrates, opening
Novel oxovanadium and dioxomolybdenum complexes of tridentate ONO-donor Schiff base ligand: Synthesis, characterization, crystal structures, Hirshfeld surface analysis, DFT computational studies and catalytic activity for the selective oxidation of benzyl
Amiri Rudbari, Hadi,Ashfaq, Muhammad,Behjatmanesh-Ardakani, Reza,Fallah-Mehrjardi, Mehdi,Forootan, Pooran,Kargar, Hadi,Nawaz Tahir, Muhammad,Shahzad Munawar, Khurram
, (2021/06/15)
Two new oxovanadium and dioxomolybdenum Schiff base complexes, [VvO(L)(OCH3)(CH3OH)] and [MoVIO2(L)(CH2CH3OH)], were synthesized by treating an ONO-donor type Schiff base ligand
Synthesis, characterization, crystal structures, Hirshfeld surface analysis, DFT computational studies and catalytic activity of novel oxovanadium and dioxomolybdenum complexes with ONO tridentate Schiff base ligand
Kargar, Hadi,Bazrafshan, Maryam,Fallah-Mehrjardi, Mehdi,Behjatmanesh-Ardakani, Reza,Rudbari, Hadi Amiri,Munawar, Khurram Shahzad,Ashfaq, Muhammad,Tahir, Muhammad Nawaz
, (2021/04/19)
For the first time, two new oxovanadium and dioxomolybdenum Schiff base complexes, VOL(OMe) and MoO2L, were synthesized through the reaction of a ONO tridentate Schiff base ligand (H2L) derived from the condensation of 5-bromosalicyl