872326-43-7

Basic information

• Product Name: (2Z,4E)-ethyl 6-(benzyloxy)hexa-2,4-dienoate
• Synonyms: (2Z,4E)-ethyl 6-(benzyloxy)hexa-2,4-dienoate
• CAS NO: 872326-43-7
• Molecular Weight: 246.306
• Mol File: 872326-43-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2Z,4E)-ethyl 6-(benzyloxy)hexa-2,4-dienoate(CAS DataBase Reference)
• NIST Chemistry Reference: (2Z,4E)-ethyl 6-(benzyloxy)hexa-2,4-dienoate(872326-43-7)
• EPA Substance Registry System: (2Z,4E)-ethyl 6-(benzyloxy)hexa-2,4-dienoate(872326-43-7)

Safety Data

• Hazardous Substances Data: 872326-43-7(Hazardous Substances Data)

Upstream product

• 69152-87-0 4-benzyloxycrotonaldehyde 
• 124755-24-4 ethyl [bis(2,2,2-trifluoroethoxy)phosphinyl]acetate 

Downstream Products

• 90700-15-5 (3aR,6R,6aR)-6-((S)-2-(benzyloxy)-1-hydroxyethyl)-2,2-dimethyldihydrofuro[3,4-d][1,3]dioxol-4(3aH)-one 
• 872326-51-7 (3R,4S,5S)-5-((S)-2'-(benzyloxy)-1'-(tert-butyl(dimethyl)silanyloxy)ethyl)-3,4-dihydroxy-4,5-dihydrofuran-2(3H)-one 
• 872326-54-0 (3aR,6S,6aR)-6-[(S)-2-Benzyloxy-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-2,2-dimethyl-dihydro-furo[3,4-d][1,3]dioxol-4-one 
• 872326-49-3 (S)-5-((S)-2'-(benzyloxy)-1'-(tert-butyl(dimethyl)silanyloxy)ethyl)furan-2(5H)-one 
• 90661-40-8 (S)-5-((S)-2'-(benzyloxy)-1-hydroxyethyl)furan-2(5H)-one 

Relevant articles and documents

A de novo asymmetric approach to achiral deoxy-melodorinol analogues

A short and highly efficient route to deoxy-Melodorinol analogues has been developed. The key to the overall transformation is the use of an enantioselective Sharpless asymmetric dihydroxylation of an (Z,E)-dienoate to control the regioselectivity of the dihydroxylation reaction and a Mitsunobu elimination reaction to control the E-stereochemistry of the,δ-double bond. The highly efficient synthesis stereoselectively prepared four analogues in 3 steps from 4-substituted crotonaldehydes.