86770-69-6

Basic information

• Product Name: Azido-PEG6
• Synonyms: Azido-PEG6;Azido-PEG6-alcohol;N3-PEG6-OH
• CAS NO: 86770-69-6
• Molecular Formula: C₁₂H₂₅N₃O₆
• Molecular Weight: 307.3434
• Mol File: 86770-69-6.mol
• Article Data: 62

Chemical Properties

• Appearance: /
• Solubility: Soluble in Water, DMSO, DCM, DMF
• CAS DataBase Reference: Azido-PEG6(CAS DataBase Reference)
• NIST Chemistry Reference: Azido-PEG6(86770-69-6)
• EPA Substance Registry System: Azido-PEG6(86770-69-6)

Safety Data

• Hazardous Substances Data: 86770-69-6(Hazardous Substances Data)

Usage

Description

Azido-PEG6, also known as Azido-PEG6-alcohol, is a water-soluble reagent that features an azide group and a terminal hydroxyl group. The azide group is capable of reacting with alkyne, BCN, and DBCO through Click Chemistry, resulting in a stable triazole linkage. The hydroxyl group allows for additional derivatization or substitution with other reactive functional groups, making Azido-PEG6 a versatile molecule for various applications.

Uses

Used in Bioconjugation:
Azido-PEG6 is used as a bioconjugation agent for the attachment of biomolecules to other molecules or surfaces. The azide group facilitates the formation of stable triazole linkages through Click Chemistry, enabling the efficient and specific binding of biomolecules.
Used in Drug Delivery Systems:
In the pharmaceutical industry, Azido-PEG6 is used as a component in drug delivery systems to improve the solubility, stability, and bioavailability of drugs. The hydroxyl group allows for the attachment of drug molecules or other functional groups, enhancing the overall performance of the drug delivery system.
Used in Materials Science:
Azido-PEG6 is utilized as a building block in the synthesis of functional polymers and materials. The azide group can be used to create cross-links or incorporate other reactive groups, while the hydroxyl group provides opportunities for further modification or attachment of specific functional groups, contributing to the development of advanced materials with tailored properties.
Used in Chemical Synthesis:
In chemical synthesis, Azido-PEG6 serves as an intermediate or reactant for the preparation of various compounds. The azide and hydroxyl groups offer multiple points of reactivity, allowing for the synthesis of a wide range of products with diverse applications.

Upstream product

• 352439-34-0 17-hydroxy-3,6,9,12,15-pentaoxaheptadec-1-yl methanesulfonate 
• 39160-70-8 3,6,9,12,15,18-hexaoxa-1-octadecyl amine 
• 139115-90-5 2-(2-azidoethoxy)ethanol 
• 77544-68-4 8-tosyloxy-3,6-dioxaoctanol 
• 86520-52-7 2-[2-(2-azidoethoxy)ethoxy]ethanol 
• 69502-33-6 2-(2-(2-((tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethyl 4-methylbenzenesulfonate 
• 136399-07-0 17-iodo-3,6,9,12,15-pentaoxaheptadecan-1-ol 
• 112-27-6 2,2'-[1,2-ethanediylbis(oxy)]bisethanol 
• 28746-78-3 17-chloro-3,6,9,12,15-pentaoxaheptadecan-1-ol 
• 2615-15-8 pentaethylene glycol 
• 98-59-9 p-toluenesulfonyl chloride 
• 1352550-66-3 17-azido-3,6,9,12,15-pentaoxaheptadecyl 2-chloroacetate 
• 112-60-7 Tetraethylene glycol 
• 37860-51-8 tetraethylene glycol di(p-toluenesulfonate) 

Downstream Products

• 906007-10-1 2[-2-(2-{2-[2-(2-azido-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethyl p-tosylate 
• 1228763-93-6 C₃₅H₆₁N₃O₁₄ 
• 1402411-90-8 17-azido-1-bromo-3,6,9,12,15-pentaoxaheptadecane 
• 1448451-77-1 C₃₅H₄₄N₄O₁₃ 
• 1448451-72-6 tert-butyl 17-azido-3,6,9,12,15-pentaoxaheptadecan-1-oate 
• 1104083-46-6 20-amino-3,6,9,12,15,18-hexaoxaicosanoic acid 
• 1448451-78-2 C₂₉H₄₄N₄O₁₂ 
• 1448451-79-3 C₃₁H₄₅F₃N₂O₁₃ 
• 1448451-80-6 C₃₁H₄₇F₃N₂O₁₃ 
• 141282-35-1 [2-(2-{2-[2-(2-amino-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]acetic acid 
• 1448451-74-8 C₂₁H₃₃N₃O₈ 
• 1446282-38-7 17-azido-3,6,9,12,15-pentaoxaheptadecanal 

Relevant articles and documents

THERAPEUTIC COMPOSITION OF CURE-PRO COMPOUNDS FOR TARGETED DEGRADATION OF BET DOMAIN PROTEINS, AND METHODS OF MAKING AND USAGE

The present application is directed to a therapeutic composition, comprising two precursor compounds (monomers) that are suitable for assembly via two or more reversible covalent bonds. The monomers are polyfunctionalized molecules comprising a bioorthogo

THERAPEUTIC CURE-PRO COMPOUNDS FOR TARGETED DEGRADATION OF BET DOMAIN PROTEINS, AND METHODS OF MAKING AND USING THEM

The present application is directed to a therapeutically useful compound, comprised of two monomers that are linked to each other through two or more reversible covalent bonds. Each monomer is a polyfunctionalized molecule comprising a bioorthogonal linker element and ligand or pharmacophore, wherein the linker and ligand/pharmacophore are covalently coupled to each other either directly or through an optional connector moiety.

Supramolecular compound nano-carrier as well as preparation method and application thereof

The invention discloses a supramolecular compound nano-carrier as well as a preparation method and application thereof, and relates to the technical field of polymer chemistry and biological detection engineering. According to the supramolecular compound nano-carrier disclosed by the invention, a two-dimensional nanosheet supramolecular structure system generated by self-assembly is driven by an anion induction effect, and a supramolecular compound nano-carrier is of a single-layer nanosheet supramolecular structure constructed by a highly-oriented one-dimensional nanorod. A hydrophobic perylene group part is used as a skeleton part for constructing the highly-oriented one-dimensional nanorod, and the charge density of a single-layer nanosheet can be regulated and controlled. The surface of the water-soluble multivalent hydrophilic part can be loaded with DNAzyme deoxyribozyme for specific detection of heavy metal ions through electrostatic interaction, and the water-soluble multivalent supramolecular compound nano sensor is constructed. Based on a fluorescence change mechanism caused by specific cutting of heavy metal ions, The fluorescence detection of the heavy metal ions in food and biological tissues is realized, and the detection effect of the heavy metal ions is greatly enhanced.