866782-59-4

Basic information

• Product Name: 8-FLUORO-3-IODOQUINOLINE
• Synonyms: 8-FLUORO-3-IODOQUINOLINE;Quinoline, 8-fluoro-3-iodo-
• CAS NO: 866782-59-4
• Molecular Formula: C₉H₅FIN
• Molecular Weight: 273.05
• Mol File: 866782-59-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 324.4 °C at 760 mmHg
• Flash Point: 150 °C
• Appearance: /
• Density: 1.908 g/cm³
• Vapor Pressure: 0.000467mmHg at 25°C
• Refractive Index: 1.696
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: -0.17±0.28(Predicted)
• CAS DataBase Reference: 8-FLUORO-3-IODOQUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 8-FLUORO-3-IODOQUINOLINE(866782-59-4)
• EPA Substance Registry System: 8-FLUORO-3-IODOQUINOLINE(866782-59-4)

Safety Data

• Hazardous Substances Data: 866782-59-4(Hazardous Substances Data)

Usage

General Description

8-Fluoro-3-iodoquinoline is a chemical compound with the molecular formula C9H5FIN. It is a substituted quinoline, which is a heterocyclic aromatic organic compound. 8-Fluoro-3-iodoquinoline is used in organic synthesis and pharmaceutical research, as its unique structure and properties make it a valuable building block for creating new chemical compounds and drug molecules. The presence of both fluorine and iodine atoms in its structure gives this compound interesting and useful reactivity, making it a versatile tool for creating new chemical compounds with diverse properties and applications. Its potential as a pharmaceutical intermediate and synthetic building block make 8-Fluoro-3-iodoquinoline a valuable compound in the field of organic chemistry and drug discovery.

InChI:InChI=1/C9H5FIN/c10-8-3-1-2-6-4-7(11)5-12-9(6)8/h1-5H

Upstream product

• 394-68-3 8-fluoroquinoline 

Downstream Products

• 866782-60-7 8-fluoro-3-(phenylsulfonyl)quinoline 
• 933792-11-1 3-[(4-chlorophenyl)sulfonyl]-8-fluoroquinoline 
• 1207750-07-9 (8-fluoroquinolin-3-yl)boronic acid 
• 933824-72-7 3-(phenylsulfonyl)-N-[2-(4-pyridinyl)ethyl]-8-quinolinamine 
• 933792-04-2 3-[(4-chlorophenyl)sulfonyl]-N-(tetrahydro-2H-pyran-4-ylmethyl)-8-quinolinamine 
• 1066836-04-1 N-(tetrahydro-2H-pyran-4-ylmethyl)-3-({4-[(tetrahydro-2H-pyran-4-ylmethyl)amino]phenyl}sulfonyl)-8-quinolinamine 

Relevant articles and documents

Method for preparing 8-fluoroquinoline and method for preparing 3-iodo-8-fluoroquinoline

The invention provides a method for preparing 8-fluoroquinoline and a method for preparing 3-iodo-8-fluoroquinoline. Preparation of the 8-fluoroquinoline comprises the step of carrying out a ring-closure reaction between fluoroaniline and glycerin, and preparation of the 3-iodo-8-fluoroquinoline comprises the step of carrying out a substitution reaction among the prepared 8-fluoroquinoline, N-chlorosuccinimide and a metal iodide. The method has the characteristics that the raw materials are cheap and readily available, the cost is low, any special equipment is not needed, the various materialsare low in toxicity, safe, environmental-friendly, less in by-products and high in yield, and large-scale industrial production is easily realized.

NOVEL QUINOLINE COMPOUNDS CAPABLE OF BINDING AT THE CB2 RECEPTOR

The present invention relates to novel quinoline derivatives such as compounds of the formula (I) which possess are capable of selectively modulating the cannabinoid 2 receptor and the use of such compounds or pharmaceutical compositions thereof in the tr

3-((HETERO)ARYLSULFONYL)-8-` (AMINOALKYL)OXY!QUINOLINES AS 5-HT6 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF CNS DISORDERS

The present invention relates to novel quinoline derivatives such as compounds of the formula (I): and the use of such compounds or pharmaceutical compositions thereof in the treatment of CNS and other disorders.