866541-93-7 Usage
General Description
AT-101 is a synthetic small molecule that belongs to the class of BH3 mimetics, which mimic the action of pro-apoptotic Bcl-2 family proteins. It has been shown to inhibit the anti-apoptotic Bcl-2 proteins, and is being investigated for its potential as a cancer treatment. AT-101 has been found to induce apoptosis in cancer cells, inhibit tumor growth, and enhance the efficacy of other chemotherapeutic agents. It has also been studied for its potential to overcome drug resistance in cancer cells. Additionally, AT-101 has shown promising results in preclinical studies for its potential to treat other diseases such as hepatitis C and HIV. Overall, AT-101 has demonstrated potential as a therapeutic agent for various diseases and is currently under investigation in clinical trials.
Check Digit Verification of cas no
The CAS Registry Mumber 866541-93-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,6,5,4 and 1 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 866541-93:
(8*8)+(7*6)+(6*6)+(5*5)+(4*4)+(3*1)+(2*9)+(1*3)=207
207 % 10 = 7
So 866541-93-7 is a valid CAS Registry Number.
866541-93-7Relevant articles and documents
A gossypol derivatives and their use in inhibiting urease activity
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Paragraph 0047; 0048; 0052; 0053, (2017/10/20)
The invention relates to the technical field of fertilizer, and particularly relates to gossypol derivatives and an application thereof in inhibition of urease activity. The gossypol derivatives have the chemical structural general formula described in the specification, wherein R represents a part except amino in amino acid, and the amino acid is amino acid containing primary amino. The gossypol derivatives take gossypol as an aldehyde group providing reagent and are prepared by modifying the aldehyde group of gossypol with the amino of the amino acid. When the gossypol derivatives are applied in preparation of urease inhibitors, the urease inhibition effect is good, and the IC50 value inhibiting soil ammonia volatilization effect is as low as 1.56*10 mol.L. Compared with a gossypol raw material, the gossypol derivatives have better solubility, are more stable and are convenient to use; and a part of gossypol derivatives have the urease inhibition activity significantly enhanced.