86608-70-0 Usage
Description
2-(1,3-Dioxolan-2-yl)ethyltriphenylphosphonium bromide is a phosphonium salt compound that features a 1,3-dioxolan-2-ylethyl group attached to a triphenylphosphonium cation. It is a versatile reagent in organic synthesis and has unique properties due to its phosphonium center and the presence of the 1,3-dioxolan-2-ylethyl moiety.
Uses
Used in the Suzuki Reaction:
2-(1,3-Dioxolan-2-yl)ethyltriphenylphosphonium bromide is used as a reagent in the Suzuki reaction for the formation of carbon-carbon bonds. Its phosphonium center facilitates the cross-coupling process, making it a valuable component in palladium-catalyzed reactions.
Used in Wittig Olefination:
In the Wittig olefination, 2-(1,3-dioxolan-2-yl)ethyltriphenylphosphonium bromide serves as a reactant to convert aldehydes and ketones into alkenes. Its unique structure contributes to the efficiency and selectivity of the olefination process.
Used in the Preparation of Ligands for Histamine Receptor Binding with H3/H4 Subtype Selectivity:
2-(1,3-Dioxolan-2-yl)ethyltriphenylphosphonium bromide is used as a building block in the synthesis of ligands targeting histamine receptors, specifically with H3 and H4 subtype selectivity. Its incorporation into ligand structures can enhance binding affinity and selectivity, which is crucial for the development of drugs with fewer side effects.
Used in the Preparation of Dual Inhibitors of Phosphodiesterase-4 and Serotonin Reuptake:
This phosphonium salt is utilized in the preparation of dual inhibitors that target both phosphodiesterase-4 and serotonin reuptake. Its presence in the molecular structure of these inhibitors can improve the therapeutic potential of drugs used in the treatment of various psychiatric and neurological disorders.
Used in Pharmaceutical Industry:
2-(1,3-Dioxolan-2-yl)ethyltriphenylphosphonium bromide is used as a synthetic intermediate for the development of new pharmaceuticals. Its unique properties and reactivity make it a valuable component in the synthesis of complex organic molecules with potential therapeutic applications.
Used in Chemical Research:
In the field of chemical research, 2-(1,3-dioxolan-2-yl)ethyltriphenylphosphonium bromide is used as a versatile reagent for exploring new reaction pathways and developing innovative synthetic methods. Its phosphonium center allows for unique interactions and transformations that can lead to the discovery of new chemical processes.
Check Digit Verification of cas no
The CAS Registry Mumber 86608-70-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,6,0 and 8 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 86608-70:
(7*8)+(6*6)+(5*6)+(4*0)+(3*8)+(2*7)+(1*0)=160
160 % 10 = 0
So 86608-70-0 is a valid CAS Registry Number.
InChI:InChI=1/C23H24O2P.BrH/c1-4-10-20(11-5-1)26(21-12-6-2-7-13-21,22-14-8-3-9-15-22)19-16-23-24-17-18-25-23;/h1-15,23H,16-19H2;1H/q+1;/p-1
86608-70-0Relevant articles and documents
Stereoselective synthesis of 3-oxygenated-ds-dialkyl-2,5-substituted tetrahydrofurans from cyclohexadienediols
Brovetto, Margarita,Seoane, Gustavo
, p. 5776 - 5785 (2008/12/21)
(Chemical Equation Presented) The 3-oxygenated-cis-dialkyl-2,5-substituted tetrahydrofuran system, present in several natural products, was prepared with good selectivity by acidic cyclization of 5-alkene-1,2,4-triol derivatives. The starting alkenol was
SYNTHESIS OF A PHOTOSYNTHETIC MODEL COMPOUND WITH A LONG ALKYL CHAIN AND ITS INCORPORATION INTO BOVINE SERUM ALBUMIN
Sakata, Yoshiteru,Hirano, Yasuhiro,Tatemitsu, Hitoshi,Misumi, Soichi,Ochiai, Hideo,Shibata, Hitoshi
, p. 4717 - 4728 (2007/10/02)
Quinone-linked porphyrin 1 having a long alkyl chain was synthesized and fixed it into bovine serum albumin (BSA) for getting the information about the effect of protein upon photosynthetic electron transfer.The complex of the reference compound 19 lacking quinone with BSA showed fluorescence, while BSA-1 did not fluoresce at all.
