86412-57-9 Usage
Description
N-(4-chloro-2-methoxyphenyl)acetamide, with the chemical formula C9H10ClNO2, is an organic compound that features a chloro and methoxy substituent on a phenyl ring, attached to an amide group. It is characterized by its unique structural properties and potential reactivity, making it a versatile building block in organic synthesis.
Uses
Used in Organic Synthesis:
N-(4-chloro-2-methoxyphenyl)acetamide is used as a synthetic intermediate for the preparation of various organic compounds. Its presence of both electron-donating and electron-withdrawing groups on the phenyl ring allows for a range of chemical reactions, facilitating the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, N-(4-chloro-2-methoxyphenyl)acetamide is utilized as a key component in the development of new drugs. Its unique structure can be further modified to create molecules with specific biological activities, potentially leading to the discovery of novel therapeutic agents.
Used in Agrochemical Industry:
N-(4-chloro-2-methoxyphenyl)acetamide also finds application in the agrochemical sector, where it can be employed to synthesize new pesticides or herbicides. Its chemical properties allow for the creation of compounds that can effectively control pests and weeds, contributing to improved crop yields and agricultural productivity.
Used in Chemical Research:
In the field of chemical research, N-(4-chloro-2-methoxyphenyl)acetamide serves as a valuable compound for studying reaction mechanisms and exploring new synthetic methodologies. Its reactivity and structural features make it an interesting subject for academic and industrial research, potentially leading to advancements in organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 86412-57-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,4,1 and 2 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 86412-57:
(7*8)+(6*6)+(5*4)+(4*1)+(3*2)+(2*5)+(1*7)=139
139 % 10 = 9
So 86412-57-9 is a valid CAS Registry Number.
86412-57-9Relevant articles and documents
HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS
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Paragraph 0324-0325, (2020/07/16)
The present disclosure relates generally to compounds useful in treatment of conditions associated with mutant isocitrate dehydrogenase (mt-IDH), particularly mutant IDH1 enzymes. Specifically, the present invention discloses compound of formula (IA), which exhibits inhibitory activity against mutant IDH1 enzymes. Method of treating conditions associated with excessive activity of mutant IDH1 enzymes with such compound is disclosed. Uses thereof, pharmaceutical composition, and kits are also disclosed.
Reexamination of the Thermolytic Rearrangement of 4-Halophenyl Azides to 2-Aminophenols and other Products
Gershon, H.,Clarke, D. D.,Gershon, M.
, p. 367 - 380 (2007/10/02)
The halogenation of derivatives of 2-aminophenol with N-chloro- and N-bromosuccinimides at ambient temperatures in acetic acid was studied.With the necessary compounds available, a reexamination of the thermolytic rearrangement of 2-halophenyl azides to 2-aminophenols and other products was undertaken.It is certain that the rearrangement of 4-halophenyl azides to 2-aminophenols occurs but the products identified in this study differ significantly from those reported previously by Suschitzky et al. (1963, 1966). Keywords: Acetylated-2-amino-5-halophenols; 2-Acetamido-5-haloanisoles; 6-Halo-2-methylbenzoxazoles; 6-Halobenzoxazolones; 6-Halotriacetylaminophenols; 1H-NMR spectra; Fungicidal activity.
