862366-28-7Relevant articles and documents
A series of stable, metastable and unstable salts of Imatinib with improved solubility
Du, Guan-Hua,Fang, Zheng-Yu,Gong, Ning-Bo,Jia, Hong-Li,Lu, Yang,Wang, Xue,Xing, Wen-Hui,Zhang, Bao-Xi
, (2022/01/19)
Pharmaceutical salt formation is the most preferred and effective method to enhance the physicochemical properties of APIs. The aim of the study was to design and synthesize a series of new salts to improve the solubility of Imatinib (IM). Two stable salt
SALT FORMS OF 4-(4-METHYLPIPERAZIN-1-YLMETHYL)-n-[4-METHYL-3-(4-PYRIDIN-3-YL)PYRIMIDIN-2-YLAMINO)PHENYL]-BENZAMIDE
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Page/Page column 5-6, (2008/06/13)
The present invention relates to acid addition salts of 4-[4-methyl-1-piperazinylmethyl]-N-[4-methyl-3-[[4-¢3-pyridinyl-2-pyrimidinyl]amino]phenyl]-benzamide, which are selected from the group consisting of a tartrate salt, such as a (D)(-) tartrate salt