85909-08-6 Usage
Description
1-(TERT-BUTOXYCARBONYL)-2-PYRROLIDINONE, also known as N-Boc-2-pyrrolidinone, is a synthetic intermediate with a tert-butoxycarbonyl group attached to the nitrogen atom of the pyrrolidinone ring. It is a versatile compound used in various chemical reactions and synthesis processes.
Uses
Used in Pharmaceutical Industry:
1-(TERT-BUTOXYCARBONYL)-2-PYRROLIDINONE is used as a synthetic intermediate for the preparation of highly functionalized N-acyl-2-vinylpyrrolidines through a 4-component Ugi reaction. This reaction involves isocyanide, carbonyl compounds, primary amines, and carboxylic acids, and is crucial for the development of new pharmaceutical compounds.
Used in Flavor and Fragrance Industry:
1-(TERT-BUTOXYCARBONYL)-2-PYRROLIDINONE is used as a precursor for the synthesis of naturally occurring Maillard flavors. These flavors are essential in the food and beverage industry for enhancing taste and aroma. The synthesis is achieved through catalytic SeO2 oxidation, which allows for the production of a wide range of flavor compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 85909-08-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,9,0 and 9 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 85909-08:
(7*8)+(6*5)+(5*9)+(4*0)+(3*9)+(2*0)+(1*8)=166
166 % 10 = 6
So 85909-08-6 is a valid CAS Registry Number.
InChI:InChI=1/C9H15NO3/c1-9(2,3)13-8(12)10-6-4-5-7(10)11/h4-6H2,1-3H3
85909-08-6Relevant articles and documents
Selective C(sp3)?H Aerobic Oxidation Enabled by Decatungstate Photocatalysis in Flow
Laudadio, Gabriele,Govaerts, Sebastian,Wang, Ying,Ravelli, Davide,Koolman, Hannes F.,Fagnoni, Maurizio,Djuric, Stevan W.,No?l, Timothy
supporting information, p. 4078 - 4082 (2018/03/21)
A mild and selective C(sp3)?H aerobic oxidation enabled by decatungstate photocatalysis has been developed. The reaction can be significantly improved in a microflow reactor enabling the safe use of oxygen and enhanced irradiation of the reaction mixture. Our method allows for the oxidation of both activated and unactivated C?H bonds (30 examples). The ability to selectively oxidize natural scaffolds, such as (?)-ambroxide, pregnenolone acetate, (+)-sclareolide, and artemisinin, exemplifies the utility of this new method.
Process and intermediates to a tetrahydro-[1,8]- Naphthyridine
-
, (2008/06/13)
A novel process is provided for the preparation of 3-(5,6,7,8-tetrahydro-[1,8]-naphthyridin-2-yl)-propylamine which is useful in the synthesis of αv integrin receptor antagonists. Also provided are useful intermediates obtained from the process.