85391-24-8

Basic information

• Product Name: 1-propylimidazolidine-2,4-dione
• Synonyms: 1-propylimidazolidine-2,4-dione;1-Propyl-2,4-imidazolidinedione;1-Propylhydantoin;Einecs 286-777-9;2,4-IMidazolidinedione, 1-propyl-
• CAS NO: 85391-24-8
• Molecular Formula: C₆H₁₀N₂O₂
• Molecular Weight: 142.1558
• EINECS: 286-777-9
• Mol File: 85391-24-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 124-127 °C
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.156g/cm³
• Refractive Index: 1.48
• PKA: 8.94±0.10(Predicted)
• CAS DataBase Reference: 1-propylimidazolidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-propylimidazolidine-2,4-dione(85391-24-8)
• EPA Substance Registry System: 1-propylimidazolidine-2,4-dione(85391-24-8)

Safety Data

• Hazardous Substances Data: 85391-24-8(Hazardous Substances Data)

Usage

Class

Imidazolidine-2,4-dione derivatives

Uses

Production of cosmetic products, moisturizing and anti-aging properties, skincare products, hair care products

Benefits

Antioxidant and anti-inflammatory effects, improves texture and appearance of the hair

Potential Applications

Pharmaceutical industry for treating skin conditions and aging-related disorders.

InChI:InChI=1/C6H10N2O2/c1-2-3-8-4-5(9)7-6(8)10/h2-4H2,1H3,(H,7,9,10)

Upstream product

• 1034186-44-1 methyl N-cyano-N-n-propylaminoacetate 
• 131543-46-9 Glyoxal 
• 627-06-5 n-propylurea 

Downstream Products

• 1053654-54-8 (2R,4S)-1-(4-Butoxy-benzenesulfonyl)-4-(2,5-dioxo-3-propyl-imidazolidin-1-yl)-pyrrolidine-2-carboxylic acid methyl ester 
• 1053698-38-6 (2R,4S)-4-(2,5-Dioxo-3-propyl-imidazolidin-1-yl)-1-[4-(2-methoxy-ethoxy)-benzenesulfonyl]-pyrrolidine-2-carboxylic acid methyl ester 

Relevant articles and documents

An efficient approach for the synthesis of N-1 substituted hydantoins

An efficient three-step route for the synthesis of N-1 alkyl/aryl- substituted hydantoins was developed from inexpensive commercially available substrates. The reaction of amines with cyanogen bromide takes place to give monoalkyl/aryl cyanamides. This on treatment with methyl bromoacetate in the presence of sodium hydride in tetrahydrofuran affords methyl N-cyano-N-alkyl/arylaminoacetate, which undergoes hydrolysis and cyclization in the presence of 50% H2SO4 to afford N-1 substituted hydantoins in very good-to-excellent yields. Wide varieties of final products having primary, secondary, tertiary, and aryl substituents at the N-1 position were successfully synthesized by this method. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.