849928-28-5

Basic information

• Product Name: 1-N-BOC-4-(3-BROMOPHENYL)-4-CYANOPIPERIDINE
• Synonyms: 1-N-BOC-4-(3-BROMOPHENYL)-4-CYANOPIPERIDINE;1-BOC-4-CYANO-4-(3-BROMOPHENYL)-PIPERIDINE;1-N-BOC-4-(3-BROMOPHENYL)PIPERIDINE-4-CARBONITRILE;1-Piperidinecarboxylic acid, 4-(3-bromophenyl)-4-cyano-, 1,1-dimethylethyl ester;tert-Butyl 4-(3-bromophenyl)-4-cyano-1-piperidinecarboxylate;1-Boc-4-Cyano-4-(3-Bromophenyl)-Piperidine(WX633026)
• CAS NO: 849928-28-5
• Molecular Formula: C₁₇H₂₁BrN₂O₂
• Molecular Weight: 365.26
• Mol File: 849928-28-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 469.6±45.0 °C(Predicted)
• Appearance: /
• Density: 1.35±0.1 g/cm3(Predicted)
• PKA: -3.50±0.40(Predicted)
• CAS DataBase Reference: 1-N-BOC-4-(3-BROMOPHENYL)-4-CYANOPIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-N-BOC-4-(3-BROMOPHENYL)-4-CYANOPIPERIDINE(849928-28-5)
• EPA Substance Registry System: 1-N-BOC-4-(3-BROMOPHENYL)-4-CYANOPIPERIDINE(849928-28-5)

Safety Data

• Hazardous Substances Data: 849928-28-5(Hazardous Substances Data)

Usage

Description

1-N-BOC-4-(3-BROMOPHENYL)-4-CYANOPIPERIDINE is a chemical compound with the molecular formula C17H20N2O2Br. It is a piperidine derivative featuring a BOC-protected amine group and a cyano functional group. The presence of a 3-bromophenyl group in the molecule endows it with potential applications in medicinal chemistry.

Uses

Used in Pharmaceutical Synthesis:
1-N-BOC-4-(3-BROMOPHENYL)-4-CYANOPIPERIDINE is used as a key building block for the synthesis of various pharmaceuticals and biologically active molecules. Its unique structure allows for the development of new drugs with specific therapeutic properties.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 1-N-BOC-4-(3-BROMOPHENYL)-4-CYANOPIPERIDINE is used as a starting material for the design and synthesis of novel compounds with potential therapeutic applications. Its versatility in chemical reactions makes it a valuable asset in drug discovery processes.
Safety Precautions:
It is important to handle and use 1-N-BOC-4-(3-BROMOPHENYL)-4-CYANOPIPERIDINE with proper safety precautions due to potential hazards associated with its use in laboratory and industrial settings.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 31938-07-5 (3-bromophenyl)acetonitrile 
• 118753-70-1 N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine 

Downstream Products

• 1211581-86-0 tert-butyl 4-amino-4-phenylpiperidine-1-carboxylate 
• 1265602-77-4 C₁₉H₂₆N₂O₂ 
• 1035345-80-2 4-cyano-4-[3-(1-methyl-1H-pyrazol-4-yl)-phenyl]-piperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

A nitrogen-containing heterocyclic phenyl piperidine compound and its preparation method and application

The invention discloses a nitrogen-containing heterocyclic phenyl piperidine compound or pharmaceutical salt thereof. The general structural formula a of the compound is as shown in specification, wherein R represents hydrogen, mono-substituted or poly-substituted halogen, methyl, methoxyl, tertiary butyl or trifluoromethyl; and R2 is hydrogen, chlorine, bromine, methyl or ethyl. The compound disclosed by the invention is novel in structure; and by introducing the active amino in the form of a piperidine ring, the configuration of the side-chain amino is reinforced and the rigidity of the compound is enhanced. Through the design transformation, the Akt1 kinase inhibitory activity and the PC-3 cell line growth inhibitory activity of the compound are significantly enhanced.

3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.