84803-52-1 Usage
Description
N-(2-chloro-6-nitrophenyl)-N-phenylacetamide, also known as Chloramphenicol, is a chemical compound belonging to the class of acetamides. It is primarily used as an antibiotic medication for the treatment of bacterial infections.
Uses
Used in Pharmaceutical Industry:
N-(2-chloro-6-nitrophenyl)-N-phenylacetamide is used as an antibiotic for the treatment of bacterial infections. It works by inhibiting protein synthesis in bacteria, thereby preventing their growth and reproduction. It is effective against a wide range of bacteria, making it a valuable and versatile antibiotic.
However, its use is restricted due to potential side effects and the development of bacterial resistance.
Check Digit Verification of cas no
The CAS Registry Mumber 84803-52-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,8,0 and 3 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 84803-52:
(7*8)+(6*4)+(5*8)+(4*0)+(3*3)+(2*5)+(1*2)=141
141 % 10 = 1
So 84803-52-1 is a valid CAS Registry Number.
InChI:InChI=1/C14H11ClN2O3/c1-10(18)16(11-6-3-2-4-7-11)14-12(15)8-5-9-13(14)17(19)20/h2-9H,1H3
84803-52-1Relevant articles and documents
A direct, regioselective palladium-catalyzed synthesis of N-substituted benzimidazoles and imidazopyridines
Alonso, Jorge,Halland, Nis,Nazare, Marc,R'Kyek, Omar,Urmann, Matthias,Lindenschmidt, Andreas
supporting information; experimental part, p. 234 - 237 (2011/03/20)
Unsymmetric, N-substituted benzimidazoles and imidazopyridines can be prepared directly from 2-halonitroarenes and amides through Pd(TFA) 2/(R)-BINAP-catalyzed cross-coupling and subsequent reductive aminocyclization. This sequence can be conducted by a one-pot procedure. The method is versatile and allows the straightforward, regioselective preparation of these important nitrogen heterocycles. Unsymmetrical, N-substituted benzimidazoles can be prepared directly from 2-halonitroarenes and amides through Pd(TFA)2/(R)-BINAP-catalyzed cross-coupling and subsequent reductive aminocyclization.This sequence can be conducted by a one-pot procedure. The method is versatile and allows the straightforward, regioselective preparation of these important nitrogen heterocycles. Copyright