83001-42-7

Basic information

• Product Name: 2,6-dicyclohexylisonicotinonitrile
• Synonyms: 2,6-dicyclohexylisonicotinonitrile
• CAS NO: 83001-42-7
• Molecular Weight: 268.402
• Mol File: 83001-42-7.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2,6-dicyclohexylisonicotinonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-dicyclohexylisonicotinonitrile(83001-42-7)
• EPA Substance Registry System: 2,6-dicyclohexylisonicotinonitrile(83001-42-7)

Safety Data

• Hazardous Substances Data: 83001-42-7(Hazardous Substances Data)

Upstream product

• 100-48-1 pyridine-4-carbonitrile 
• 108-85-0 1-bromocyclohexane 
• 110-82-7 cyclohexane 
• 626-62-0 Cyclohexyl iodide 
• 98-89-5 Cyclohexanecarboxylic acid 

Relevant articles and documents

Metal-free radical-mediated C(sp3)-H heteroarylation of alkanes

Herein we disclose a metal-free, N/O-centered radical-promoted Minisci reaction, in which the coupling of various heteroarenes with simple alkanes proceeds under mild conditions. The reaction conditions are neutral; no extra acid is added to preactivate N

Benzoyl peroxide promoted radical ortho-alkylation of nitrogen heteroaromatics with simple alkanes and alcohols

A catalytic amount of benzoyl peroxide (BPO)-initiated cross-dehydrogenative coupling reaction of N-iminopyridine ylides with simple alkanes and alcohols leads to the corresponding 2-alkylpyridines with high regioselectivity in moderate to good yields without an additional reduction step to remove the activated group. A catalytic amount of benzoyl peroxide (BPO)-initiated cross-dehydrogenative coupling reaction of N-iminopyridine ylides with simple alkanes and alcohols has been developed. The strategy allowed convenient access to various 2-alkylpyridines in moderate to good yields without an additional reduction step to remove the activated group.

Polar Effects in Free-Radical Reactions. Homolytic Heteroaromatic Substitutions by Alkyl Bromides

Alkyl bromides have been utilized for the first time as radical sources for heteroaromatic substitution.A variety of procedures was revealed to be successful for bromine abstraction: Bu3SnH with AIBN, (Me3Si)3SiH with AIBN, Ph2SiH2, or Et3SiH associated with peroxides (H2O2, t-BuOOH, (t-BuO)2, (t-BuOOCO)2, (PhCOO)2).The importance of the polar effects is discussed.