82671-06-5 Usage
Description
2,6-Dichloro-5-fluoronicotinic acid, also known as 2,6-Dichloro-5-fluoropyridine-3-carboxylic acid, is a halogenated heterocyclic compound with a molecular structure that features two chlorine atoms at the 2nd and 6th positions and a fluorine atom at the 5th position on a pyridine ring. It has a reported density of 1.6207g/cm3 at 25°C. 2,6-Dichloro-5-fluoronicotinic acid is known for its potential applications in various fields, particularly in the study of protein interactions and the development of self-assembled monolayers.
Uses
Used in Biochemical Research:
2,6-Dichloro-5-fluoronicotinic acid is used as a reagent for modulating protein-protein interactions. It aids researchers in understanding the mechanisms involved in amyloid assembly, which is crucial for studying diseases associated with protein misfolding and aggregation.
Used in Material Science:
In the field of material science, 2,6-Dichloro-5-fluoropyridine-3-carboxylic acid is utilized in the preparation of self-assembled monolayers (SAMs). These SAMs are essential in creating well-ordered molecular films on surfaces, which have applications in nanotechnology, electronics, and sensor development due to their unique properties and customizable surface functionalities.
Check Digit Verification of cas no
The CAS Registry Mumber 82671-06-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,6,7 and 1 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 82671-06:
(7*8)+(6*2)+(5*6)+(4*7)+(3*1)+(2*0)+(1*6)=135
135 % 10 = 5
So 82671-06-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H6BrFO2/c1-12-8(11)5-2-3-7(10)6(9)4-5/h2-4H,1H3
82671-06-5Relevant articles and documents
ANTIVIRAL AND ANTIMICROBIAL COMPOUNDS
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Paragraph 0128; 0129, (2014/03/25)
Disclosed are guanidine and biguanidine derivatives which have anti-viral and antibacterial activity. Also disclosed are pharmaceutical compositions containing such compounds as an active ingredient, and anti-viral and anti-bacterial methods utilizing such compounds. Methods of treating infections using the guanidine and biguanidine derivatives are also disclosed.
Process for the synthesis of 2,6-dichloro-5-fluoronicotinic acid and 2,6-dichloro-5-fluoronicotinoyl chloride
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, (2008/06/13)
An improved process for the preparation of 2,6-dichloro-5-fluoronicotinoyl chloride is described where a 2,6-dihydroxy-5-fluoronicotinic acid ester is converted in one step using phosphorus oxychloride and a lithium reagent to 2,6-dichloro-5-fluoronicotinoyl chloride and subsequent basic hydrolysis affords 2,6-dichloro-5-fluoronicotinic acid.
Fluorinated pyrido[2,3-c]pyridazines. I. Reductive cyclization of ethyl 2-diazo-2-(5-fluoro-2-hal-onicotinoyl)acetate with trialkylphosphine
Miyamoto,Matsumoto
, p. 3211 - 3217 (2007/10/02)
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