82304-66-3

Basic information

• Product Name: 7,9-ditert-butyl-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione
• Synonyms: 7,9-ditert-butyl-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione;1-Oxaspiro[4.5]deca-6,9-diene-2,8-dione, 7,9-bis(1,1-dimethylethyl)-
• CAS NO: 82304-66-3
• Molecular Formula: C₁₇H₂₄O₃
• Molecular Weight: 276.37066
• Mol File: 82304-66-3.mol
• Article Data: 7

Chemical Properties

• Melting Point: 139-140 °C
• Boiling Point: 426.3±45.0 °C(Predicted)
• Appearance: /
• Density: 1.06±0.1 g/cm3(Predicted)
• Storage Temp.: Amber Vial, -20°C Freezer, Under inert atmosphere
• Solubility: Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
• Stability: Light Sensitive
• CAS DataBase Reference: 7,9-ditert-butyl-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 7,9-ditert-butyl-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione(82304-66-3)
• EPA Substance Registry System: 7,9-ditert-butyl-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione(82304-66-3)

Safety Data

• Hazardous Substances Data: 82304-66-3(Hazardous Substances Data)

Usage

Health Benifits

7,9-Ditert-butyl-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione belongs to flavonoid compound. It can be found in morels (Morchella spp.), which are among the most valuable and important mushrooms because of their taste and commercial value. It can be identified as one of bioactive compounds in whole plant extract of Euphorbia pulcherrima, which are used in folk medicine to treat skin diseases, gonorrhea, migraine, intestinal parasites, and warts. In addition, 7,9-ditert-butyl-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione can also be found in marine algae, which have been highly acknowledged to possess noticeable pharmacological activities, including antineoplastic, antimicrobial and antiviral activities due to their specific functional compounds (which are not available in other plants).

Chemical Properties

7,9-Ditert-butyl-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione (C17H24O3, CAS registry No. 82304-66-3) is an oxaspiro compound that is 1-oxaspiro[4.5]deca-6,9-diene-2,8-dione carrying two additional tert-butyl substituents at positions 7 and 9. It is an oxaspiro compound with a lactone, an enone and a cyclic ketone. Its melting point is 139-140 °C.

Uses

7,9-Di-tert-butyl-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione is an antioxidant naturally found in aerial parts of Gmelina asiatica Linn (Verbenaceae). It is also found in essential oils of some Stachys species from Mediterranean area. It is an impurity of Irganox 1098 (A697523) used in the food packaging.

Upstream product

• 65849-91-4 methyl 3-(3,5-di-tert-butyl-1-hydroperoxy-4-oxocyclohexa-2,5-dien-1-yl)propanoate 
• 20170-32-5 4-hydroxy-3,5-di-tert-butylphenylpropionic acid 
• 6386-38-5 methyl 3-(4-hydroxy-3,5-di-tert-butyl)phenylpropanoate 
• 67-56-1 methanol 
• 75-05-8 acetonitrile 
• 26347-98-8 pentaerythritol ester of 4-hydroxy-3,5-di-tert-butylphenylpropionic acid 
• 99591-64-7 3-(1-Amino-3,5-di-tert-butyl-4-oxo-cyclohexa-2,5-dienyl)-propionic acid 

Downstream Products

• 99591-64-7 3-(1-Amino-3,5-di-tert-butyl-4-oxo-cyclohexa-2,5-dienyl)-propionic acid 
• 95602-92-9 3,5-di-tert-butyl-4-hydroxycinnamic acid 
• 20170-32-5 4-hydroxy-3,5-di-tert-butylphenylpropionic acid 
• 147167-96-2 ethyl ester of trans-4-hydroxy-3,5-di-tert-butylcinnamic acid 
• 50394-07-5 methyl ester of trans-4-hydroxy-3,5-di-tert-butylcinnamic acid 

Relevant articles and documents

OMS Letters. Mass Spectral Studies of 7,9-di-tert-butyl-1-oxaspirodeca-6,9-diene-2,8-dione

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A singlet oxygen approach to oxaspirocycles

A method for the preparation of oxygen containing spirocycles using singlet oxygen is reported. A series of phenols were converted into the corresponding peroxy-cyclohexadienone derivatives by irradiation with visible light in the presence of a sensitizer and oxygen. The resulting peroxides could be converted into ether and lactone spirocycles in one or two steps. The synthesis of the oxaspirocycles from the phenols can also be performed in a one-pot fashion, avoiding the isolation of the peroxide intermediates.

REACTION OF 6,8-DI-TERT-BUTYL-1-OXASPIRODECA-5,8-DIENE-2,7-DIONE WITH AMINES

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